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Key Documents

D199

Supelco

Dimethcathinone hydrochloride

Synonym(s):

(±)-2-Dimethylamino-1-phenyl-1-propanone hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C11H15NO · HCl
CAS Number:
Molecular Weight:
213.70
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:

drug control

USDEA Schedule I; Home Office Schedule 1; regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

solubility

H2O: soluble

format

neat

SMILES string

Cl.CC(N(C)C)C(=O)c1ccccc1

InChI

1S/C11H15NO.ClH/c1-9(12(2)3)11(13)10-7-5-4-6-8-10;/h4-9H,1-3H3;1H

InChI key

APOWZIQNQJSLKG-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Sympathomimetic CNS stimulant; exhibits amphetamine-like effects.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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S L Markantonis et al.
The Journal of pharmacy and pharmacology, 38(7), 515-519 (1986-07-01)
The absorption of diethylpropion (DEP I), dimethylpropion (DMP I) and some of their basic metabolites into and passage through the skin was investigated and a comparison of their metabolism following oral and percutaneous administration made. High percentages (60-80%) of DEP
S L Markantonis et al.
Biochemical medicine and metabolic biology, 42(1), 1-8 (1989-08-01)
A study of the in vitro metabolism of dimethylpropion using different tissue homogenates of certain animals showed that: 1. Only the two major metabolites of dimethylpropion, i.e., methylpseudoephedrine and monomethylpropion were formed. 2. Species variation was observed with regard to
M Pokrajac et al.
Rapid communications in mass spectrometry : RCM, 5(2), 59-61 (1991-02-01)
Complex metabolic mixtures of 2-aminopropiophenones, obtained both after in vitro and human in vivo metabolism of these compounds, have been investigated using both mass spectrometry and gas chromatography/mass spectrometry. The mass spectrometric fragmentation schemes of the compounds have been proposed
W E Soholing
Fortschritte der Medizin, 100(7), 289-293 (1982-02-18)
We treated 30 patients between 22 to 30 years of age, who showed static labile circulatory disturbances of blood pressure. We carried out a double blind study following a two week schedule using for treatment an "indirect" sympathomimeticum Dimepropion-HCI. Control
The stereoselective metabolism of dimethylpropion and monomethylpropion.
S L Markantonis et al.
Biochemical pharmacology, 35(3), 529-532 (1986-02-01)

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