D1814

Anti-DcR3 antibody produced in rabbit

~0.5 mg/mL, IgG fraction of antiserum, buffered aqueous solution

• Synonym(s): Anti-Decoy Receptor 3, Anti-TNFRSF6B, Anti-TR6
• MDL number: MFCD02686088
• UNSPSC Code: 12352203

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: IgG fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 33 kDa
• species reactivity: mouse, rat, human
• concentration: ~0.5 mg/mL
• technique(s): microarray: suitable; western blot: 1:500-1:1,000 using human heart, brain or kidney lysates
• UniProt accession no.: O95407
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... TNFRSF6B(8771) ; mouse ... Dcr3(497118)

Description

General description

It is a member of the tumor necrosis factor receptor superfamily (TR6). DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues.

Immunogen

synthetic peptide corresponding to amino acids 31-46 of human DcR3 precursor.

Application

Anti-DcR3 antibody produced in rabbit is suitable for western blotting at a working dilution of 1:500-1:1000 using human heart, brain or kidney lysates.

Biochem/physiol Actions

DcR3 is a soluble decoy receptor that binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis.

Physical form

Solution in 0.01 M phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.