β-Casomorphin Fragment 1-5 (BCM5), an opioid receptor agonist, is a member of the β-casomorphin peptide family derived from β-casein. β-casomorphins are used to study their differential effects on processes such as hyperglycemia, oxidative stress, opioid signalling and immunosuppression.
Bioscience, biotechnology, and biochemistry, 67(11), 2501-2504 (2003-12-04)
The effects of intracerebroventricular (i.c.v.) injection of bovine beta-casomorphin-5 (beta-CM-5: Tyr-Pro-Phe-Pro-Gly), a micro-opioid agonist derived from milk beta-casein, on step-down type passive avoidance tasks were investigated in mice. Intracerebroventricular administration of a high dose (10 microg) of beta-CM-5 produced a
International journal of peptide and protein research, 48(1), 102-111 (1996-07-01)
The conformational properties of three cyclic beta-casomorphin analogs based on the general formula H-Tyr-c[-D-Orn-2-Nal-D-Pro-Xaa-] (2-Nal = 2-naphthylalanine; Xaa = D-Ala, Sar or NMe-Ala) in DMSO solution were investigated using NMR spectroscopy in conjunction with molecular modeling techniques. The D-Ala5- and
[Affect of peptide and non-peptide opioids on the defensive reaction of the cockroach Periplaneta americana in the "hot chamber"].
O B Gritsaĭ et al.
Zhurnal evoliutsionnoi biokhimii i fiziologii, 40(2), 125-130 (2004-07-29)
Effects of beta-casomorphin on 3H-ouabain binding to guinea pig heart membranes.
The beta -casomorphin-5 sequence was systematically modified by substitution of the naturally occurring amino acids. The derivatives are compared on the basis of their affinities towards mu 1-, mu 2 and delta -opioid binding sites estimated by means of binding
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