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T5411

Supelco

Testosterone solution

1.0 mg/mL in 1,2-dimethoxyethane, drug standard

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About This Item

CAS Number:
58-22-0
Beilstein:
1915399
MDL number:
MFCD00003654
UNSPSC Code:
41116107
PubChem Substance ID:
329826822
NACRES:
NA.24

grade

drug standard

Quality Level

200

drug control

Home Office Schedule 4.2

concentration

1.0 mg/mL in 1,2-dimethoxyethane

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

2-8°C

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@@H](O)CC[C@@]24[H]

InChI

1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1

InChI key

MUMGGOZAMZWBJJ-DYKIIFRCSA-N

Gene Information

human ... AR(367) , EBP(10682) , ESR1(2099) , PGR(5241) , SERPINA6(866) , SHBG(6462)
mouse ... Esr1(13982)
rat ... Ar(24208) , Esr1(24890) , Nr3c1(24413) , Nr3c2(25672) , Pgr(25154)

Related Categories

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Signal Word

Danger

Hazard Statements

H225,H315,H332,H360FD

Hazard Classifications

Acute Tox. 4 Inhalation - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2

Supplementary Hazards

EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

41.0 °F - closed cup

Flash Point(C)

5 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000366470
0000310882
0000310882
0000320401
0000308713

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Testosterone-2,3,4-13C3 solution 0.1 mg/mL in methanol, 99 atom % 13C, 98% (CP)

Sigma-Aldrich

730610

Testosterone-2,3,4-13C3 solution

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Annu A Söderholm et al.
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We studied the three-dimensional quantitative structure-activity relationships (3D QSAR) of 70 structurally and functionally diverse androgen receptor (AR) binding compounds using the comparative molecular similarity indices analysis (CoMSIA) method. The compound set contained 67 nonsteroidal analogues of flutamide, nilutamide, and
Line Cantin et al.
The Journal of biological chemistry, 282(42), 30910-30919 (2007-08-23)
Antiandrogens are commonly used to treat androgen-dependent disorders. The currently used drugs unfortunately possess very weak affinity for the human AR (hAR), thus indicating the need to develop new high-affinity steroidal antiandrogens. Our compounds are specially designed to impede repositioning
Peng Cui et al.
Bioorganic & medicinal chemistry letters, 16(13), 3401-3405 (2006-05-03)
Lisofylline (LSF, 1-(5-R-hydroxyhexyl)-3,7-dimethylxanthine) is an anti-inflammatory agent that protects beta-cells from Th1 cytokine-induced dysfunction and reduces the onset of Type 1 diabetes in non-obese diabetic (NOD) mice. Due to its low potency, poor oral bioavailability, and short half-life, the widespread
Jenny Roy et al.
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In our efforts to develop compounds with therapeutic potential as antiandrogens, we synthesized a series of 5alpha-androstane-3alpha,17beta-diol derivatives with a fixed side-chain length of 3-methylenes at C-16alpha, but bearing a diversity of functional groups at the end. Among these, the
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