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M3637

Supelco

Methaqualone hydrochloride

analytical standard

Synonym(s):

2-Methyl-3-(2-methylphenyl)-4(3H)-quinazolinone hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C16H14N2O · HCl
CAS Number:
340-56-7
Molecular Weight:
286.76
EC Number:
206-431-2
MDL number:
MFCD00058185
UNSPSC Code:
41116107
PubChem Substance ID:
24896861
NACRES:
NA.24

grade

analytical standard

drug control

USDEA Schedule I; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Cl.Cc1ccccc1N2C(C)=Nc3ccccc3C2=O

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Sedative/hypnotic that displaces diazepam from its binding site on the GABAA receptor inducing cytochrome P-450 and UDP-glucuronyltransferase activity.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Precautionary Statements

P301 + P310

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
125F0510

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S Buyuktimkin et al.
Journal of pharmaceutical sciences, 81(11), 1092-1094 (1992-11-01)
Locomotor activity-inhibiting, anticonvulsant, muscle relaxant, analgesic, and antimicrobial properties of 2-methyl-3-pyridinium-acetylamino-4(3H)-quinazolinone chloride (1), 2-methyl-3-(4-methylpyridinium)acetylamino-4(3H)-quinazolinone chloride (2), 2-methyl-3-(4-ethylpyridinium)acetylamino-4(3H)-quinazolinone chloride (3), 2-methyl-3-(3-carboxamidopyridinium)acetylamino-4(3H)-quinazolinon e chloride (4), and 2-methyl-3-(4-carboxamidopyridinium)-acetylamino-4(3H)- quinazolinone chloride (5) were investigated. The locomotor activity-inhibiting properties and anticonvulsant activity of 2 were

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