82400
Ethylene glycol monopropyl ether
puriss., ≥99.0% (GC)
Synonym(s):
2-Propoxyethanol, Propyl glycol
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About This Item
Linear Formula:
CH3CH2CH2OCH2CH2OH
CAS Number:
Molecular Weight:
104.15
Beilstein:
1731983
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
vapor pressure
1.3 mmHg ( 20 °C)
grade
puriss.
Assay
≥99.0% (GC)
refractive index
n20/D 1.413 (lit.)
n20/D 1.413
bp
150-153 °C (lit.)
mp
−75 °C (lit.)
density
0.913 g/mL at 25 °C (lit.)
SMILES string
CCCOCCO
InChI
1S/C5H12O2/c1-2-4-7-5-3-6/h6H,2-5H2,1H3
InChI key
YEYKMVJDLWJFOA-UHFFFAOYSA-N
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Eye Irrit. 2 - Flam. Liq. 3
Storage Class Code
3 - Flammable liquids
WGK
WGK 1
Flash Point(F)
118.4 °F - closed cup
Flash Point(C)
48 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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R Loch-Caruso et al.
Environmental health perspectives, 57, 119-123 (1984-08-01)
Intercellular communication most likely plays a significant coordinating role in morphogenesis. Blockage of a specific type of intercellular communication, that mediated by gap junctions, has been proposed as a mechanism of action of some teratogens. Several glycol ethers have recently
W J Krasavage et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 15(3), 517-527 (1990-10-01)
To determine the potential developmental toxicity of ethylene glycol monopropyl ether (EGPE), groups of pregnant New Zealand white rabbits were exposed to target concentrations of 0, 125, 250, or 500 ppm EGPE vapors for 6 hr a day on Days
W J Krasavage et al.
Teratology, 32(1), 93-102 (1985-08-01)
In order to determine the potential developmental toxicity of ethylene glycol monopropyl ether (EGPE), pregnant rats were exposed to vapor concentrations of 100, 200, 300, or 400 ppm of the compound for 6 hours per day on days 6-15 of
G V Katz et al.
Environmental health perspectives, 57, 165-175 (1984-08-01)
The acute toxicity of ethylene glycol monopropyl ether (EGPE) and ethylene glycol monopropyl ether acetate (EGPEA) was determined in a series of standardized tests. The oral LD50 in rats was 3089 and 9456 mg/kg EGPE and EGPEA, respectively. Skin irritation
Jochem Louisse et al.
Toxicological sciences : an official journal of the Society of Toxicology, 118(2), 470-484 (2010-09-14)
At present, regulatory assessment of systemic toxicity is almost solely carried out using animal models. The European Commission's REACH legislation stimulates the use of animal-free approaches to obtain information on the toxicity of chemicals. In vitro toxicity tests provide in
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