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04-921

Sigma-Aldrich

Anti-GluR6/7 Antibody, clone NL9, rabbit monoclonal

culture supernatant, clone NL904, Upstate®

Synonym(s):

Anti-EAA4, Anti-GLR6, Anti-GLUK6, Anti-GLUR6, Anti-GluK2, Anti-MRT6, Anti-NEDLAS

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

culture supernatant

antibody product type

primary antibodies

clone

NL904, monoclonal

species reactivity

mouse, rat, human

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_021956

UniProt accession no.

Q13002

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... GRIK2(2898)

Specificity

Recognizes GluR6/7.

Immunogen

KLH-conjugated, synthetic peptide corresponding to amino acids 894-908 (C-terminus) of rat GluR6. The immunizing sequence is identical in human.

Application

Anti-GluR6/7 Antibody, clone NL9 is an antibody against GluR6/7 for use in IP & WB.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Quality

Routinely evaluated by immunoblot analysis.

Target description

115 kDa

Linkage

Replaces: 05-921

Physical form

None

Storage and Stability

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Mouse brain tissue, rat brain microsomal preparation, human brain lysates

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Neto auxiliary protein interactions regulate kainate and NMDA receptor subunit localization at mossy fiber-CA3 pyramidal cell synapses.
Wyeth, MS; Pelkey, KA; Petralia, RS; Salter, MW; McInnes, RR; McBain, CJ
The Journal of Neuroscience null
Gerti Beliu et al.
Communications biology, 2, 261-261 (2019-07-26)
Genetic code expansion (GCE) technology allows the specific incorporation of functionalized noncanonical amino acids (ncAAs) into proteins. Here, we investigated the Diels-Alder reaction between trans-cyclooct-2-ene (TCO)-modified ncAAs, and 22 known and novel 1,2,4,5-tetrazine-dye conjugates spanning the entire visible wavelength range.
Evidence for a role of glutamate as an efferent transmitter in taste buds.
Vandenbeuch A, Tizzano M, Anderson CB, Stone LM, Goldberg D, Kinnamon SC
BMC Neuroscience null
Mapping the Ligand Binding Sites of Kainate Receptors: Molecular Determinants of Subunit-Selective Binding of the Antagonist [3H]UBP310.
Atlason PT, Scholefield CL, Eaves RJ, Mayo-Martin MB, Jane DE, Molnar E
Molecular Pharmacology null
Qiu-Ju Zhu et al.
FEBS letters, 586(9), 1259-1264 (2012-04-10)
Protein SUMOylation has been implicated in the pathogenesis of ischemic stroke. However, the underlying mechanisms remain unclear. Here, we found that global brain ischemia evokes a sustained elevation of GluK2 SUMOylation in the rat hippocampal CA1 region. Over-expression of wild-type
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