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850408P

Avanti

4ME 16:0 PS

1,2-diphytanoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

Synonym(s):

1,2-di-(3,7,11,15-tetramethylhexadecanoyl)-sn-glycero-3-phospho-L-serine (sodium salt); PS(16:0(3me,7me,11me,15me)/16:0(3me,7me,11me,15me))

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About This Item

Empirical Formula (Hill Notation):
C46H89NO10PNa
CAS Number:
474967-76-5
Molecular Weight:
870.16
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (850408P-10mg)
pkg of 1 × 25 mg (850408P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850408P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)COC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O.[Na+]

General description

4ME 16:0 PS (1,2-diphytanoyl-sn-glycero-3-phospho-L-serine) is a sodium salt of a fatty acid modified lipid.

Application

4ME 16:0 PS (1,2-diphytanoyl-sn-glycero-3-phospho-L-serine (sodium salt)) may be used as a component in planar lipid bilayer and in asymmetrical leaflets to study the translocation of β-galactosidase (β-gal) across an asymmetric bilayer. It may be used as an internal standard in electrospray ionization-mass spectrometry (ESI-MS/MS) analysis.

Biochem/physiol Actions

Diphytanoyl lipids are mainly used in electrophysiological experiments.

Packaging

5 mL Clear Glass Sealed Ampule (850408P-10mg)
5 mL Clear Glass Sealed Ampule (850408P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Description
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Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Extraction and profiling of plant polar glycerol lipids
Liu Y and Wang X
Bio-protocol, 6(10), 1849e-1849e null
Elsa Bárány-Wallje et al.
Biophysical journal, 89(4), 2513-2521 (2005-07-26)
Penetratin is a short, basic cell-penetrating peptide able to induce cellular uptake of a vast variety of large, hydrophilic cargos. We have reassessed the highly controversial issue of direct permeation of the strongly cationic peptide across negatively charged lipid membranes.
Xin Li et al.
Analytical chemistry, 89(22), 12369-12374 (2017-10-21)
Pep-1 is a cell-penetrating peptide that represents a powerful strategy for delivering large, hydrophilic therapeutic molecules into cells. Model membranes, such as lipid vesicles and planar bilayers, have been useful for investigating the direct translocation of cell-penetrating peptides. Here, we
Alessio Sacconi et al.
Langmuir : the ACS journal of surfaces and colloids, 34(40), 12183-12190 (2018-09-16)
Solid supported membranes (SSMs) are usually formed by an hybrid octadecanethiol/phosphatidylcholine (PC) bilayer supported by a gold electrode. Recently, it was shown that phosphatidylserine (PS) in place of PC can promote a more effective accumulation of lipid vesicles on the
Sezgin Kara et al.
Biochimica et biophysica acta. Biomembranes, 1859(10), 1828-1837 (2017-06-08)
The branched chains in diphytanoyl lipids provide membranes with unique properties, such as high chemical/physical stability, low water permeability, and no gel-to-fluid phase transition at ambient temperature. Synthetic diphytanoyl phospholipids are often used as model membranes for electrophysiological experiments. To
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