810314P

NBD Phytosphingosine

Omega-NBD D-ribo-Phytosphingosine, powder

• Synonym(s): (2S,3S,4R)-2-amino-18-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)octadecane-1,3,4-triol
• Empirical Formula (Hill Notation): C₂₄H₄₁N₅O₆
• CAS Number: 2260669-58-5
• Molecular Weight: 495.61
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 100 μg (810314P-100ug); pkg of 1 × 250 μg (810314P-250ug); pkg of 1 × 50 μg (810314P-50ug)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 810314P
• shipped in: dry ice
• storage temp.: −20°C

Description

General description

Phytosphingosine (PHS) is one of the important constituent of phytoceramides. This sphingoid has a hydroxyl group at C-4 of the sphingoid long-chain base. PHS is a component of mammalian epidermis and is widely distributed in fungi and plants. Nitrobenzoxadiazole/7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) is a fluorescent conjugate.

Application

NBD Phytosphingosine has been used as a substrate in ceramide synthase assays.

Biochem/physiol Actions

Phytosphingosine (PHS) is capable of activating G-protein coupled receptor 120 (GPR120). Treating cultured keratinocytes (KC) with PHS can enhance the content of ceramide NP. It plays as key role in epidermal differentiation and also possesses anti-inflammatory and antimicrobial activities.

Packaging

5 mL Amber Glass Screw Cap Vial (810314P-100ug)

5 mL Amber Glass Screw Cap Vial (810314P-250ug)

5 mL Amber Glass Screw Cap Vial (810314P-50ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3