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810144C

Avanti

16:0 NBD PE

Avanti Research™ - A Croda Brand 810144C

Synonym(s):

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl) (ammonium salt)

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1 MG
€240.00
5 MG
€382.00

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1 MG
€240.00
5 MG
€382.00

About This Item

Empirical Formula (Hill Notation):
C43H78N5O11P
CAS Number:
384823-46-5
Molecular Weight:
872.08
MDL number:
MFCD02063886
UNSPSC Code:
12352211
NACRES:
NA.25

€240.00

Please contact Customer Service for Availability
Request a Bulk Order

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810144C-1mg)
pkg of 5 × 1 mL (810144C-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810144C

concentration

1 mg/mL (810144C-1mg)
1 mg/mL (810144C-5mg)

shipped in

dry ice

storage temp.

−20°C

General description

16:0 NBD PE is a headgroup labelled fluorescent phospholipid. Phosphatidylethanolamine (PE) is the most abundant phospholipid in bacteria and the second most abundant in animals, plants and yeast.[1]

Application

16:0 NBD PE is suitable:
  • for use in the bilayer, as fluorescent probe, together with encapsulated doxorubicin (DXR)[2] for the preparation of planar-supported lipid bilayers (PSLB) of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)
  • used in fluorescence control experiment[3]
  • for labelling giant plasma membrane vesicles[4]

Biochem/physiol Actions

L-α-Phosphatidylethanolamine maintains membrane integrity.[5]

Packaging

5 mL Amber Glass Screw Cap Vial (810144C-1mg)
5 mL Amber Glass Screw Cap Vial (810144C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

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Federico Mazur et al.
Langmuir : the ACS journal of surfaces and colloids (2020-02-26)
Synthetic micromotors are evaluated extensively in a range of biomedical, microscale transport, and environmental applications. Fundamental insight into micromotors that exhibit locomotion due to triggered disintegration of their associated liposomes is provided. Directed self-propulsion is observed when the lipid vesicles
1, 2-diacyl-phosphatidylcholine flip-flop measured directly by sum-frequency vibrational spectroscopy
Liu J and Conboy JC
Biophysical Journal, 89(4), 2522-2532 (2005)
Structural determinants for partitioning of lipids and proteins between coexisting fluid phases in giant plasma membrane vesicles
Sengupta P, et al.
Biochimica et Biophysica Acta - Biomembranes, 1778(1), 20-32 (2008)
Mesha Saeed et al.
International journal of nanomedicine, 14, 2069-2089 (2019-04-17)
Melanoma is the most aggressive form of skin cancer. Chemotherapy at a late stage fails due to low accumulation in tumors, indicating the need for targeted therapy. To increase drug uptake by tumor cells, we have targeted doxorubicin-containing liposomes using
Sathish Ramakrishnan et al.
eLife, 9 (2020-05-14)
Calcium (Ca2+)-evoked release of neurotransmitters from synaptic vesicles requires mechanisms both to prevent un-initiated fusion of vesicles (clamping) and to trigger fusion following Ca2+-influx. The principal components involved in these processes are the vesicular fusion machinery (SNARE proteins) and the
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