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S5200

Sigma-Aldrich

Suberic acid

98%

Synonym(s):

Octanedioic acid

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5 G
€26.60
100 G
€44.30
500 G
€117.00

About This Item

Linear Formula:
HOOC(CH2)6COOH
CAS Number:
Molecular Weight:
174.19
Beilstein:
1210161
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

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Assay

98%

bp

230 °C/15 mmHg (lit.)

mp

139-146 °C
140-144 °C (lit.)

SMILES string

OC(=O)CCCCCCC(O)=O

InChI

1S/C8H14O4/c9-7(10)5-3-1-2-4-6-8(11)12/h1-6H2,(H,9,10)(H,11,12)

InChI key

TYFQFVWCELRYAO-UHFFFAOYSA-N

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Application

Suberic acid can be used to synthesize:
  • Perfluorinated analogs of suberoyl anilide hydroxamic acid (SAHA) as potent histone deacetylase inhibitors.[1]
  • Hemiester analogs of pregnenolone sulfate (PES).[2]
  • Cellulose acetate suberate, a cellulose ω-carboxyalkanoate.[3]
  • It can also act as a cross-linker for poly(vinyl alcohol) (PVA). The cross-linked molecule shows enhanced tensile strength when compared to neat PVA.[4]

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

410.0 °F - closed cup

Flash Point(C)

210 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Rifampin stability and solution concentration enhancement through amorphous solid dispersion in cellulose ω-carboxyalkanoate matrices.
Arca H C, et al.
Journal of Pharmaceutical Sciences, 107(1), 127-138 (2018)
Crosslinking of Polyvinyl Alcohol (PVA) and Effect of Crosslinker Shape (Aliphatic and Aromatic) Thereof.
Sonker A K, et al.
Journal of Polymers and the Environment, 26(5), 1782-1794 (2018)
Positive Modulators of the N-Methyl-d-aspartate Receptor: Structure?Activity Relationship Study of Steroidal 3-Hemiesters.
Krausova B, et al.
Journal of Medicinal Chemistry, 61(10), 4505-4516 (2018)
Larisa Sheihet et al.
Biomacromolecules, 6(5), 2726-2731 (2005-09-13)
We describe the synthesis and characterization of a family of biocompatible ABA-triblock copolymers that comprised of hydrophilic A-blocks of poly(ethylene glycol) and hydrophobic B-blocks of oligomers of suberic acid and desaminotyrosyl-tyrosine esters. The triblock copolymers spontaneously self-assemble in aqueous solution
Perfluorinated HDAC inhibitors as selective anticancer agents.
Walton J W, et al.
Organic & Biomolecular Chemistry, 15(43), 9186-9190 (2017)

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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