QBD10722

Hydroxy-dPEG^®₂₄-t-butyl ester

>90% (HPLC)

• Synonym(s): HO-PEG₂₄-CO-Otbu, HO-PEG₂₄-TBE, Hydroxy-PEG-t-butyl ester, Hydroxy-PEG₂₄-t-butyl-ester, PEG₁₀₀₀-t-butyl ester
• Empirical Formula (Hill Notation): C₅₅H₁₁₀O₂₇
• Molecular Weight: 1203.45
• MDL number: MFCD13185018
• UNSPSC Code: 12352108
• NACRES: NA.22

Properties

• Assay: >90% (HPLC)
• form: solid or viscous liquid
• reaction suitability: reaction type: Pegylations
• polymer architecture: shape: linear; functionality: heterobifunctional
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: O(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
• InChI key: YMILISGQCISYOH-UHFFFAOYSA-N

Description

Features and Benefits

Hydroxy-dPEG₂₄-t-butyl ester is a versatile building block based upon a monodispersed polyethylene glycol (PEG) chain, comparable to a polymeric PEG₁₀₀₀. The single molecular weight, discrete-length PEG (dPEG) chain is 86 atoms (88.5 Å) long. A primary alcohol group terminates one end of the molecule. The opposite end is a propionic acid group protected as the tert-butyl ester. The terminal hydroxy group can be functionalized with various reactive groups to permit direct modification of surfaces, small molecules, or biomolecules. The tert-butyl ester deprotects with trifluoroacetic acid (TFA), exposing the terminal propionic acid, which can then be activated as the NHS or TFP ester or directly coupled to an amine using a suitable carbodiimide.

Legal Information

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable