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O3132

Sigma-Aldrich

Oxibendazole

~98%

Synonym(s):

Methyl (5-propoxy-1H-benzimidazol-2-yl)carbamate

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About This Item

Empirical Formula (Hill Notation):
C12H15N3O3
CAS Number:
20559-55-1
Molecular Weight:
249.27
EC Number:
243-877-7
MDL number:
MFCD00133728
UNSPSC Code:
12352100
PubChem Substance ID:
57654481
NACRES:
NA.22

Assay

~98%

Quality Level

100

storage temp.

2-8°C

SMILES string

CCCOc1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O3/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

InChI key

RAOCRURYZCVHMG-UHFFFAOYSA-N

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Biochem/physiol Actions

Anthelminthic

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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G W Lubega et al.
Biochemical pharmacology, 41(1), 93-101 (1991-01-01)
The low- and high-affinity binding of tritiated benzimidazole anthelmintics (mebendazole and oxibendazole) to tubulin-containing supernatants derived from unembryonated eggs, third stage larvae or adult worms of thiabendazole-susceptible and -resistant strains of Haemonchus contortus were examined and compared. The displacement of
S E Bunch
The Veterinary clinics of North America. Small animal practice, 23(3), 659-670 (1993-05-01)
Historical aspects, mechanisms, and treatment of hepatotoxicity associated with pharmacologic agents in dogs and cats are discussed. All agents that cause clinically relevant drug-induced hepatotoxicity have been reviewed within the last 5 years; therefore, only selected drugs that more recently
P A Overgaauw et al.
The Veterinary quarterly, 20(2), 69-72 (1998-05-01)
The anthelmintic efficacy and safety of the oxibendazole component in a combination oxibendazole-niclosamide paste were investigated in dogs and cats and in litters of pups with naturally acquired nematode infections. A single dose of 15 mg oxibendazole/kg body weight given
A field evaluation of three methods of administration of anthelminthics to horses.
C Uhlinger et al.
Equine veterinary journal, 24(6), 487-488 (1992-11-01)
S C Tolliver et al.
American journal of veterinary research, 54(6), 908-913 (1993-06-01)
Critical tests were conducted in horses (n = 11) with naturally acquired infections of benzimidazole (BZ)-resistant population-B small strongyles in 1989 and 1990. Anthelmintics administered were thiabendazole (44 mg/kg of body weight, n = 4), oxibendazole (10 mg/kg, n =
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