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About This Item
Linear Formula:
CF3C6H4B(OH)2
CAS Number:
Molecular Weight:
189.93
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.22
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Assay
≥95.0%
form
solid
mp
111-114 °C (lit.)
functional group
fluoro
SMILES string
OB(O)c1ccccc1C(F)(F)F
InChI
1S/C7H6BF3O2/c9-7(10,11)5-3-1-2-4-6(5)8(12)13/h1-4,12-13H
InChI key
JNSBEPKGFVENFS-UHFFFAOYSA-N
Application
2-(Trifluoromethyl)phenylboronic acid can be used as a reactant:
- In Suzuki-coupling reactions to prepare 2-trifluoromethyl aryl or heteroaryl derivatives.[1]
- To synthesize 4-(2-trifluoromethyl)phenylpyrrolo[2,3-d]pyrimidine as a potential antagonist of corticotropin-releasing hormone.[2]
- To prepare 2-nitro-6-(trifluoromethyl)phenylboronic acid by nitration reaction.[3]
Other Notes
Contains varying amounts of anhydride
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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