Skip to Content
Merck
All Photos(2)

Documents

240613

Sigma-Aldrich

2-Chloropropane

≥99%

Synonym(s):

Isopropyl chloride

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
(CH3)2CHCl
CAS Number:
75-29-6
Molecular Weight:
78.54
Beilstein:
1730782
EC Number:
200-858-8
MDL number:
MFCD00000867
UNSPSC Code:
12352100
PubChem Substance ID:
24854424
NACRES:
NA.22

vapor pressure

28.11 psi ( 55 °C)
8.59 psi ( 20 °C)

Assay

≥99%

form

liquid

refractive index

n20/D 1.378 (lit.)

bp

34-36 °C (lit.)

mp

−118 °C (lit.)

solubility

alcohol: miscible(lit.)
diethyl ether: miscible(lit.)
water: slightly soluble(lit.)

density

0.859 g/mL at 25 °C (lit.)

SMILES string

CC(C)Cl

InChI

1S/C3H7Cl/c1-3(2)4/h3H,1-2H3

InChI key

ULYZAYCEDJDHCC-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

2-Chloropropane decomposes by first-order reaction to give hydrogen chloride and propylene.

Application

2-Chloropropane can be used as a reactant:
  • In the Friedel-Crafts alkylation reaction of difluorobenzene and toluene using solid acid and methylalumoxane catalysts, respectively.
  • To prepare 4-amino-3-iodo-1-(isopropyl)pyrazolo[3,4-d]pyrimidine, a key intermediate for the synthesis of PfPK7 kinase inhibitors.
  • To prepare benzylisopropylphenylphosphine.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H302 + H312 + H332

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

-32.8 °F

Flash Point(C)

-36 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis and resolution of benzylisopropylphenylphosphine, a monodentate P-chiral ligand
Albert J, et al.
Tetrahedron Asymmetry, 11(16), 3335-3343 (2000)
Solid acid catalysts for the efficient synthesis of 2-(2, 4-difluorophenyl) propane
Hu X, et al.
Applied Catalysis A: General, 209(1-2), 117-123 (2001)
Synthesis of 3-(1, 2, 3-triazol-1-yl)-and 3-(1, 2, 3-triazol-4-yl)-substituted pyrazolo [3, 4-d] pyrimidin-4-amines via click chemistry: potential inhibitors of the Plasmodium falciparum PfPK7 protein kinase
Klein M, et al.
Organic & Biomolecular Chemistry, 7(17), 3421-3429 (2009)
MAO-catalyzed Friedel-Crafts reactions of toluene with chloroalkanes and with propylene
Kuwabara J, et al.
J. Mol. Catal. A: Chem., 208(1-2), 39-44 (2004)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service