233021

4-(Trifluoromethyl)phenylacetic acid

97%

• Synonym(s): (α,α,α-Trifluoro-p-tolyl)acetic acid
• Linear Formula: CF₃C₆H₄CH₂CO₂H
• CAS Number: 32857-62-8
• Molecular Weight: 204.15
• Beilstein: 2267687
• EC Number: 251-263-5
• MDL number: MFCD00004352
• UNSPSC Code: 12352100
• PubChem Substance ID: 24853947
• NACRES: NA.22

Properties

• Assay: 97%
• form: solid
• mp: 82-85 °C (lit.)
• SMILES string: OC(=O)Cc1ccc(cc1)C(F)(F)F
• InChI: 1S/C9H7F3O2/c10-9(11,12)7-3-1-6(2-4-7)5-8(13)14/h1-4H,5H2,(H,13,14)
• InChI key: HNORVZDAANCHAY-UHFFFAOYSA-N

Description

General description

4-(Trifluoromethyl)phenylacetic acid undergoes diolefination mediated by mono-N-protected amino acid ligands in the presence of ethyl acrylate, Pd(OAc)₂, KHCO₃ and t-amyl alcohol.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves