121967

Aminoacetaldehyde dimethyl acetal

99%

• Synonym(s): 2,2-Dimethoxyethylamine
• Linear Formula: NH₂CH₂CH(OCH₃)₂
• CAS Number: 22483-09-6
• Molecular Weight: 105.14
• Beilstein: 741868
• EC Number: 245-026-5
• MDL number: MFCD00008135
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847473
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 99%
• refractive index: n20/D 1.417 (lit.)
• bp: 135-139 °C/95 mmHg (lit.)
• density: 0.965 g/mL at 25 °C (lit.)
• SMILES string: COC(CN)OC
• InChI: 1S/C4H11NO2/c1-6-4(3-5)7-2/h4H,3,5H2,1-2H3
• InChI key: QKWWDTYDYOFRJL-UHFFFAOYSA-N

Description

General description

Aminoacetaldehyde dimethyl acetal reacts with sulfone, followed by hydrolysis and reductive amination by adding desired piperazine derivative to yield piperazine derivatives of 2-furanyl[1,2,4]triazolo[1,5-a][1,3,5]triazine.

Aminoacetaldehyde dimethyl acetal is used as a building block for the synthesis of various acylated and sufonylated oxyenamides.

Application

Aminoacetaldehyde dimethyl acetal was used in a study to develop a fluorescent substrate for aldehyde dehydrogenase. It was used in preparation of chitosan-dendrimer hybrids having various functional groups such as carboxyl, ester and poly(ethylene glycol). It was used in an efficient 3-step synthesis of a bicyclic proline analog from L-ascorbic acid and in 3-component reaction catalyzed by MgClO₄ leading to α-aminophosphonates.

Safety Information

• Pictograms: GHS02,GHS05
• Signal Word: Danger
• Hazard Statements: H226,H314
• Precautionary Statements: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Flam. Liq. 3 - Skin Corr. 1B
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 111.2 °F - closed cup
• Flash Point(C): 44 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves