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Key Documents

P9287

Sigma-Aldrich

Anti-Mouse IgG (whole molecule)–R-Phycoerythrin antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

GoatAnti-Mouse IgG (whole molecule)–R-PE

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

goat

conjugate

phycoerythrin (R-PE) conjugate

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

buffered aqueous solution

technique(s)

indirect immunofluorescence: 1:20

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

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General description

Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice . Anti-Mouse IgG (whole molecule)-R-Phycoerythrin antibody detects mouse IgG subclasses G1, G2a, G2b, and G3 and also reacts with mouse IgA and IgM by Ouchterlony Double Diffusion (ODD).

Specificity

Binds all mouse Igs.

Immunogen

Purified mouse IgG

Application

Anti-Mouse IgG (whole molecule)-R-Phycoerythrin antibody is suitable for use in flow cytometry . The antibody can also be used for indirect immunofluorescence (1:20).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 0.1 mM EDTA, 1 mM iodoacetamide, 1% bovine serum albumin and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Structure and Function of Human and Murine Receptors for IgG
Unkeless, J.C., et al.
Annual Review of Immunology, 6, 251-281 (1989)
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Journal of vascular research, 43(4), 338-346 (2006-05-31)
The remarkable patency of internal mammary artery (MA) grafts compared to saphenous vein (SV) grafts has been related to different biological properties of the two blood vessels. We examined whether proliferation and apoptosis of vascular smooth muscle cells (VSMC) from
Benjamin P Roscoe et al.
Journal of molecular biology, 426(15), 2854-2870 (2014-05-28)
The complexity of biological interaction networks poses a challenge to understanding the function of individual connections in the overall network. To address this challenge, we developed a high-throughput reverse engineering strategy to analyze how thousands of specific perturbations (encompassing all
Ga-Bin Park et al.
Oncology letters, 16(4), 4526-4536 (2018-09-15)
Treatment with celecoxib and bortezomib as single chemotherapeutic agents reduces the viability and proliferation of colorectal cancer cells. The use of these agents in combination with other chemotherapeutic agents is usually associated with adverse effects. In the present study, a
Congxing Lin et al.
Development (Cambridge, England), 136(23), 3959-3967 (2009-11-13)
Genital tubercle (GT) initiation and outgrowth involve coordinated morphogenesis of surface ectoderm, cloacal mesoderm and hindgut endoderm. GT development appears to mirror that of the limb. Although Shh is essential for the development of both appendages, its role in GT

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