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Key Documents

G7387

Sigma-Aldrich

Gly-His-Lys acetate salt

BioXtra, γ-irradiated, suitable for cell culture

Synonym(s):

Liver cell growth factor

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About This Item

Linear Formula:
C14H24N6O4C2H4O2
CAS Number:
Molecular Weight:
400.43
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.77

biological source

synthetic (organic)

Quality Level

sterility

γ-irradiated

product line

BioXtra

form

powder

mol wt

400.43 g/mol

packaging

pkg of 5 mg

technique(s)

cell culture | mammalian: suitable

impurities

<2 EU/mL

color

white

solubility

H2O: soluble 0.5 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

CC(O)=O.NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CN)C(O)=O

InChI

1S/C14H24N6O4.C2H4O2/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9;1-2(3)4/h7-8,10-11H,1-6,15-16H2,(H,17,18)(H,19,21)(H,20,22)(H,23,24);1H3,(H,3,4)/t10-,11-;/m0./s1

InChI key

MGNUTAFMLGJBGV-ACMTZBLWSA-N

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Amino Acid Sequence

Gly-His-Lys

Application

Gly-His-Lys acetate salt has been used:
  • as a component of the serum-containing medium to culture human thyroid cells
  • as a supplement to culture fisher rat thyroid cells
  • as a component of the Dulbecco′s modified Eagle Medium (DMEM)/HamF12/mesenchymal stem cell media to culture mesenchymal stem cells

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Lars Kayser et al.
Acta histochemica, 107(1), 31-41 (2005-05-04)
The objective was to investigate glucose-6-phosphate dehydrogenase (G6PD) activity in monolayer cultures of thyroid epithelial cells and to examine whether inhibition of nitric oxide synthase affects activity of G6PD or oxygen sensitivity of the assay. Primary cultures without TSH addition
Hosny Salama et al.
Stem cell research & therapy, 5(3), 70-70 (2014-06-03)
We have assessed the utility of autologous mesenchymal stem cell (MSC) peripheral vein infusion as a possible therapeutic modality for patients with end-stage liver diseases. Forty patients with post-hepatitis C virus (HCV) end-stage liver disease were randomized into two groups:
Lena Mazurowska et al.
Journal of cosmetic science, 59(1), 59-69 (2008-03-20)
This study concerning the permeability through skin barriers of copper complexes with peptides is an important part of the research on their biological activity. The transport of copper complexes through the skin is essential in treatment of dermatological dysfunctions connected
I Taci Cangul et al.
Veterinary dermatology, 17(6), 417-423 (2006-11-07)
In this study the clinical and histopathological effects of topically applied tripeptide-copper complex (TCC) and zinc oxide on open-wound healing in rabbits was evaluated. Eighteen New Zealand rabbits were divided into three groups: TCC, zinc oxide and no treatment. One
Jeffrey D Pollard et al.
Archives of facial plastic surgery, 7(1), 27-31 (2005-01-19)
To evaluate the effects of copper tripeptide (GHK-Cu) on the growth and autocrine production of basic fibroblast growth factor, transforming growth factor beta1, and vascular endothelial growth factor by normal and irradiated fibroblasts in a serum-free in vitro environment. Primary

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