Once the solution is prepared, it should be stored in separate packages to prevent product failure due to repeated freezing and thawing. The recommended storage period for the stock solution is as follows: when stored at -80°C, it should be used within 6 months; when stored at -20°C, it should be used within 1 month. To enhance solubility, the tube can be heated to 37°C and then agitated in an ultrasonic bath for a period of time.
E8515
β-Estradiol 3-benzoate
≥97%
Synonym(s):
1,3,5(10)-Estratriene-3,17β-diol 3-benzoate, 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-benzoate, 3-Benzoyloxy-17β-estrol
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About This Item
Empirical Formula (Hill Notation):
C25H28O3
CAS Number:
Molecular Weight:
376.49
Beilstein:
3107526
EC Number:
MDL number:
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥97%
Pricing and availability is not currently available.
Recommended Products
Quality Level
Assay
≥97%
mp
191-198 °C (lit.)
SMILES string
[H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])CCc4cc(OC(=O)c5ccccc5)ccc24
InChI
1S/C25H28O3/c1-25-14-13-20-19-10-8-18(28-24(27)16-5-3-2-4-6-16)15-17(19)7-9-21(20)22(25)11-12-23(25)26/h2-6,8,10,15,20-23,26H,7,9,11-14H2,1H3/t20-,21-,22+,23+,25+/m1/s1
InChI key
UYIFTLBWAOGQBI-BZDYCCQFSA-N
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Application
β-Estradiol 3-benzoate has been used:to mimic estradiol in rat during the oestrous cycle in rats.[1] It has also been used along with progesterone for the induction of sexual receptivity in female rat.[2]
Used in a study of general steroid metabolism and clearing, as groundwork for anabolic steroid screening in athletes.
Biochem/physiol Actions
β-Estradiol 3-benzoate is a synthetic estrogen. It favors breast cancer progression.[3] It is an endocrine disrupting chemicals. It interacts with endocrine system and cause harmful effect on reproduction in animals and humans. It binds to estrogen receptors and favors tumor metastatis in breast, prostate and bone cells.[4]
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 2 - Repr. 1B
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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