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128082

Sigma-Aldrich

2-Ethoxyethanol

ReagentPlus®, 99%

Synonym(s):

Ethyl glycol, Ethylene glycol monoethyl ether

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About This Item

Linear Formula:
C2H5OCH2CH2OH
CAS Number:
110-80-5
Molecular Weight:
90.12
Beilstein:
1098271
EC Number:
203-804-1
MDL number:
MFCD00002869
UNSPSC Code:
12352112
PubChem Substance ID:
329749884
NACRES:
NA.21

vapor density

3.1 (vs air)

Quality Level

200

vapor pressure

3.8 mmHg ( 20 °C)

product line

ReagentPlus®

Assay

99%

form

liquid

autoignition temp.

460 °F

expl. lim.

14 %

technique(s)

UV/Vis spectroscopy: suitable

impurities

<0.10% water

refractive index

n20/D 1.407 (lit.)

bp

135 °C (lit.)

mp

−90 °C (lit.)

solubility

water: miscible

density

0.93 g/mL at 25 °C (lit.)

SMILES string

CCOCCO

InChI

1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3

InChI key

ZNQVEEAIQZEUHB-UHFFFAOYSA-N

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General description

2-Ethoxyethanol is a glycol ether. It has been reported as a precursor for ethoxyacetic acid (EAA). Various physical properties (density, refractive index, viscosity and speed of sound) of its binary mixtures with n-alkanes, 2,2,4-trimethylpentane and cyclohexane have been evaluated. High-pressure vapor-liquid equilibrium (VLE) data of its binary mixtures with CO2 have been reported. It can be used as a solvent in the spectrophotometric determination of iron(III) by using the ligand, N,N-bis(2-hydroxy-5-bromo-benzyl)1,2 diaminopropane (HBDAP).

Application

2-Ethoxyethanol (Ethylene glycol monoethyl ether) has been used in zebrafish embryotoxicity test (ZET). It can act like a co-surfactant in the separation of highly hydrophobic analytes via microemulsion electrokinetic chromatography and solvent-modified micellar electrokinetic chromatography.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Statements

H226,H302,H331,H360FD

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3 - Repr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

104.0 °F - closed cup

Flash Point(C)

40 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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"Comparison of microemulsion electrokinetic chromatography and solvent-modified micellar electrokinetic chromatography"
Hansen HS, et al.
Journal of Separation Science, 24(8), 643-650 (2001)
"Selective preconcentration, separation and speciation of ferric iron in different samples using N, N'-bis (2-hydroxy-5-bromo-benzyl) 1, 2 diaminopropane"
Kara D and Alkan
Talanta, 55(2), 415-423 (2001)
Measurements and correlation of high-pressure VLE of binary CO2-alcohol systems (methanol, ethanol, 2-methoxyethanol and 2-ethoxyethanol).
Joung SN, et al.
Fluid Phase Equilibria, 185(1), 219-230 (2001)
Density, Viscosity, Refractive Index, and Speed of Sound in Binary Mixtures of 2-Ethoxyethanol with n-Alkanes (C6 to C12), 2, 2, 4-Trimethylpentane, and Cyclohexane in the Temperature Interval 298.15-313.15 K.
Aminabhavi TM and Gopalakrishna B.
Journal of Chemical and Engineering Data, 40(3), 632-641 (1995)
Matthew J Traynor et al.
Toxicology and applied pharmacology, 218(2), 128-134 (2006-12-19)
Glycol ethers are solvents widely used alone and as mixtures in industrial and household products. Some glycol ethers have been shown to have a range of toxic effects in humans following absorption and metabolism to their aldehyde and acid metabolites.
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