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B5524

Supelco

Benzydamine hydrochloride

analytical standard

Synonym(s):

1-Benzyl-3-(3-[dimethylamino]propoxy)-1H-indazole

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About This Item

Empirical Formula (Hill Notation):
C19H23N3O · HCl
CAS Number:
132-69-4
Molecular Weight:
345.87
EC Number:
205-076-0
MDL number:
MFCD00078957
UNSPSC Code:
41116107
PubChem Substance ID:
329773263
NACRES:
NA.24

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

SMILES string

Cl.CN(C)CCCOc1nn(Cc2ccccc2)c3ccccc13

InChI

1S/C19H23N3O.ClH/c1-21(2)13-8-14-23-19-17-11-6-7-12-18(17)22(20-19)15-16-9-4-3-5-10-16;/h3-7,9-12H,8,13-15H2,1-2H3;1H

InChI key

HNNIWKQLJSNAEQ-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742) , PTGS2(5743)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
0000257025
0000254328
035K0816
124K1460
114K1229

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N R Patil et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(5), 1985-1991 (2011-07-01)
Fluorescence quenching of biologically active carboxamide namely (E)-2-(4-chlorobenzylideneamino)-N-(2-chlorophenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide [ECNCTTC] by aniline and carbon tetrachloride (CCl4) quenchers in different solvents using steady state method and time resolved method using only one solvent has been carried out at room temperature to understand
S Y Karavana Hizarcioğlu et al.
International journal of oral and maxillofacial surgery, 40(9), 973-978 (2011-05-10)
The aim of this study was to investigate the effect of benzydamine hydrochloride bioadhesive gel on healing of oral mucosal ulceration in an animal model. For in vivo determination of the effects of the bioadhesive gel, 36 rabbits were separated
Yadira X Perez-Paramo et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 28(2), 311-320 (2018-11-02)
The major mode of metabolism of nicotine is by hydroxylation via cytochrome P450 (CYP) 2A6, but it can also undergo glucuronidation by UDP-glucuronosyltransferases and oxidation by flavin monooxygenases (FMO). The goal of this study was to examine the potential importance
F Capolongo et al.
Journal of veterinary pharmacology and therapeutics, 33(4), 341-346 (2010-07-22)
Benzydamine (BZ), a weak base and an indazole derivative with analgesic and antipyretic properties used in human and veterinary medicine, is metabolized in human, rat, cattle and rabbit to a wide range of metabolites. One of the main metabolites, BZ
S Rossi et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 74(2), 248-254 (2009-10-27)
The aim of the present work was the development of a thermally sensitive mucoadhesive gel based on chitosan derivatives for the treatment of oral mucositis. Trimethyl chitosan (TMC) and methylpyrrolidinone chitosan (MPC) were considered. They were mixed with glycerophosphate (GP)
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