The PYROMAT® System is a ready-to-use, in vitro solution for pyrogen testing, using the Monocyte Activation Test (MAT). It is based on the Mono-Mac-6 cell line and interleukin 6 (IL-6) read-out. The human monocytes that encounter pyrogens from contaminated sample, produce cytokines (IL-6), which can be detected with an enzyme-linked immunosorbent assay (ELISA). The kit contains the reagents needed to prepare the sample, perform the incubation with the monocytic cells, and the reagents needed for the ELISA detection.
Application
The PYROMAT® System is used to ensure the safety of parenteral pharmaceutical products and medical devices.
Features and Benefits
Ready-to-use kit
Components
96-well plate, Endotoxin free water, RMPI culture medium
IL-6 ELISA kit and plate
Storage and Stability
2-8°C
Recommended products
To be used with PYROMAT® cells (PYR0MATCELLS), Reference standard endotoxin (144.161.0001), NEP controls (MATHKSA, MATFLAGELLIN) and IL6 control (PYR0MATIL6)
Legal Information
PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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