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M68423

Sigma-Aldrich

N-Methyl-phenethylamine

99%

Synonym(s):

N-Methyl-2-phenylethylamine

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About This Item

Linear Formula:
C6H5CH2CH2NHCH3
CAS Number:
589-08-2
Molecular Weight:
135.21
Beilstein:
636347
EC Number:
209-632-3
MDL number:
MFCD00008291
UNSPSC Code:
12352100
PubChem Substance ID:
24897119
NACRES:
NA.22

Quality Level

100

Assay

99%

form

liquid

refractive index

n20/D 1.516 (lit.)

bp

203 °C (lit.)

density

0.93 g/mL at 25 °C (lit.)

SMILES string

CNCCc1ccccc1

InChI

1S/C9H13N/c1-10-8-7-9-5-3-2-4-6-9/h2-6,10H,7-8H2,1H3

InChI key

SASNBVQSOZSTPD-UHFFFAOYSA-N

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Application

N-Methyl-phenethylamine can be used as a reactant:
  • To synthesize N-methyl-phenethylamine based tertiary amines by reacting with different alkyl halides in the presence of triphenylphosphine (TPP) and diisopropylazocarboxylate (DIAD) via N-alkylation reaction.
  • To fabricate photochemically stable, super-sensitive, and highly selective fluorescent film for the detection of N-methamphetamine (an illicit drug).
  • To prepare biologically active squaric acid N-hydroxylamide amide derivatives.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H318

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fabrication of a new fluorescent film and its superior sensing performance to N-methamphetamine in vapor phase
H Meixia, et al.
Sensors and Actuators B, Chemical, 227 (2016)
D Reid et al.
Pharmacology, biochemistry, and behavior, 24(6), 1547-1553 (1986-06-01)
The discriminative stimulus (cue) properties of phenylethylamine (PEA) were analysed in rodents in a conventional two lever FR10 operant drug discrimination task. Rats trained to discriminate phenylethylamine at 30 mg/kg showed complete dose-related generalization to PEA and to two potential
H E Shannon et al.
The Journal of pharmacology and experimental therapeutics, 222(1), 52-60 (1982-07-01)
beta-Phenylethylamine and phenylethanolamine are biogenic amines structurally related to amphetamine which are known to occur endogenously in trace amounts in mammalian brain. The purpose of the present experiments was to determine whether these endogenous biogenic amines, like amphetamine, have reinforcing
D Kloos et al.
Journal of chromatography. A, 1232, 19-26 (2011-08-25)
The analysis of cellular metabolic processes is of fundamental biological interest. Cellular metabolites, such as the intermediates of the tricarboxylic acid (TCA) cycle, provide essential information about the metabolic state of the cell. Not only is the TCA cycle a
H E Shannon et al.
The Journal of pharmacology and experimental therapeutics, 223(1), 190-196 (1982-10-01)
Single i.v. doses of beta-phenylethylamine (PEA) and its N-methyl homolog (NMPEA) were administered to separate groups of five dogs. The dose- and time-related effects of these compounds were determined on pupil diameter, heart rate and body temperature. Blood samples were
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