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Key Documents

926639

Sigma-Aldrich

Upconversion Nanoparticles

NaYF4:Yb,Tm@NaYF4, Oil soluble core shell, 980 excitation, blue light

Synonym(s):

UCNPs

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About This Item

UNSPSC Code:
11101711
NACRES:
NA.23

Quality Level

100

concentration

5 mg/mL in cyclohexane

matrix active group

oleic acid surface treatment

particle size

30 nm±5 nm

fluorescence

λex 980 nm (blue)
λem 360 nm
-450 nm
-470 nm

storage temp.

2-8°C

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Application

Upconversion nanoparticles (ucnps), are the result of a unique optical process in which near-infrared (NIR) light excitation is converted into visable and/or UV emission. Upconversion (UC) utilizes sequential absorption of multiple photons utilizing both lifetime and real ladder-like energy levels of ions in a host lattice to produce a higher energy anti-Stokes luminescence.

This optical features of UCNPs, results in deep tissue penetration and minimal autofluorescence background, for a broad range of applications of UCNP in diagnostics and biomedical imaging systems.

Applications include:

Fluorescent microscopy
Deep-tissue bioimaging
Nanomedicine
Optogenetics
Security labelling
Volumetric display

Signal Word

Danger

Hazard Statements

H225,H304,H315,H336,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

-4.0 °F - closed cup

Flash Point(C)

-20 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics
Chen G, et al.
Chemical Reviews, 114, 5161-5214 (2014)
Amplified stimulated emission in upconversion nanoparticles for super-resolution nanoscopy
Liu, Y. et al.
Nature, 543, 229-233 (2017)
Engineering bright sub-10-nm upconverting nanocrystals for single-molecule imaging
Gargas, D. J. et al
Nature Nanotechnology, 9, 300-305 (2014)
Advances in highly doped upconversion nanoparticles
Wen, S., Zhou, J., Zheng, K. et al.
Nature Communications, 9, 2415-2415 (2018)
Christoph Drees et al.
Angewandte Chemie (International ed. in English), 55(38), 11668-11672 (2016-08-12)
Upconversion nanoparticles (UCNPs) convert near-infrared into visible light at much lower excitation densities than those used in classic two-photon absorption microscopy. Here, we engineered <50 nm UCNPs for application as efficient lanthanide resonance energy transfer (LRET) donors inside living cells. By

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