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144657

Sigma-Aldrich

Trifluoroacetamide

97%

Synonym(s):

2,2,2-Trifluoroacetamide

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About This Item

Linear Formula:
CF3CONH2
CAS Number:
354-38-1
Molecular Weight:
113.04
Beilstein:
1753625
EC Number:
206-559-9
MDL number:
MFCD00008008
UNSPSC Code:
12352100
PubChem Substance ID:
24848677
NACRES:
NA.22

Assay

97%

form

solid

bp

162.5 °C (lit.)

mp

65-70 °C (lit.)

functional group

amide

SMILES string

NC(=O)C(F)(F)F

InChI

1S/C2H2F3NO/c3-2(4,5)1(6)7/h(H2,6,7)

InChI key

NRKYWOKHZRQRJR-UHFFFAOYSA-N

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General description

Trifluoroacetamide is a good quencher of tryptophan fluorescence.

Application

Trifluoroacetamide was used as probe for determination of membrane potential and extra/intracellular volume of erythrocytes by fluorine-19 NMR studies.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Trifluoroacetamide was found to be a good quencher of tryptophan fluorescence, and the quenching was shown to proceed via both a dynamic and a static process. The respective quenching constants were determined by the measurement of the decrease of the
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