Unfortunately, the stability of this product once resuspended has not been determined.
SML2148
Sulfo-N-succinimidyl Oleate sodium
≥95% (HPLC)
Synonym(s):
(Z)-1-(oleoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid, sodium salt, (Z)-2,5-Dioxo-1-[(1-oxo-9-octadecenyl)oxy]-3-pyrrolidinesulfonic acid, sodium salt, 2,5-Dioxo-1-[[(9Z)-1-oxo-9-octadecenyl]oxy]-3-pyrrolidinesulfonic acid, sodium salt, SSO sodium salt, Sulfosuccinimidyl oleate sodium
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About This Item
Empirical Formula (Hill Notation):
C22H36NO7S· Na
CAS Number:
Molecular Weight:
481.58
EC Number:
MDL number:
UNSPSC Code:
51111800
NACRES:
NA.77
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Assay
≥95% (HPLC)
form
powder
storage condition
desiccated
under inert gas
color
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
−20°C
SMILES string
CCCCCCCC/C=C\CCCCCCCC(ON1C(C(CC1=O)S([O-])(=O)=O)=O)=O.[Na+]
InChI
1S/C22H37NO7S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(25)30-23-20(24)18-19(22(23)26)31(27,28)29;/h9-10,19H,2-8,11-18H2,1H3,(H,27,28,29);
InChI key
IENDXPSKPJDQKO-UHFFFAOYSA-N
Application
Biochem/physiol Actions
Covalently modifies fatty acid translocase (CD36/FAT) Lys164 and irreversibly inhibits CD36-dependent FA uptake in vitro and in vivo.
SSO is an inhibitor of the respiratory chain happening in mitochondria.[3] SSO targets the lysine 164 residue of the fatty acid binding site, observed in CD36 (cluster of differentiation 36), a scavenger receptor.[4]
Sulfo-N-succinimidyl oleate (SSO; Sulfosuccinimidyl oleate) inhibits fatty acid translocase (CD36/FAT)-mediated signaling as well as long-chain fatty acid (LCFA) and oxidized low density lipoproteins (oxLDL) uptake in an irreversible manner via covalent modification of CD36 Lys164 within its FA- and oxLDL-binding domain. SSO is employed both in cultures (5-500 μM) and in animals in vivo (40 mg/kg i.p.) for studying CD36-mediated cellular and physiological functions.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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After I resuspend this product ( SML2148)in DMSO, how should I store the solution? Aliquot and store at -20C?
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