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N7382

Sigma-Aldrich

Nitrosomorpholine

Synonym(s):

NMOR

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About This Item

Empirical Formula (Hill Notation):
C4H8N2O2
CAS Number:
59-89-2
Molecular Weight:
116.12
MDL number:
MFCD00039710
UNSPSC Code:
41116105
PubChem Substance ID:
24897824
NACRES:
NA.25

form

solid

SMILES string

O=NN1CCOCC1

InChI

1S/C4H8N2O2/c7-5-6-1-3-8-4-2-6/h1-4H2

InChI key

ZKXDGKXYMTYWTB-UHFFFAOYSA-N

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Biochem/physiol Actions

Tumor initiator in rodent liver, trachea, nasal cavity, esophagus, kidney, lung, and thyroid.

Packaging

Bulk package

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H301,H351

Hazard Classifications

Acute Tox. 3 Oral - Carc. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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W Lijinsky et al.
In vivo (Athens, Greece), 5(2), 85-89 (1991-03-01)
A number of nitrosamines that have been studied by administration to rats as solutions in drinking water have been examined by gavage administration of similar doses, for assessment of the role of pharmacokinetics in organ-specific carcinogenesis. Methylnitrosoethylamine was more effective
W Lijinsky et al.
Carcinogenesis, 3(8), 911-915 (1982-01-01)
A comparison was made of the carcinogenic effectiveness of some cyclic nitrosamines containing oxygen in the ring. The compounds were administered to F344 rats at approximately equimolar concentrations in drinking water. Nitrosomorpholine, nitroso-1,3-oxazolidine and nitrosotetrahydro-1,3-oxazine were of similar potency and
Lionel Ho et al.
Water research, 45(11), 3461-3472 (2011-05-03)
Granular media filtration was evaluated for the removal of a suite of chemical contaminants that can be found in wastewater. Laboratory- and pilot-scale sand and granular activated carbon (GAC) filters were trialled for their ability to remove atrazine, estrone (E1)
Jack W Winter et al.
Gastroenterology, 133(1), 164-174 (2007-07-17)
Nitrate ingestion leads to high luminal concentrations of nitric oxide being generated where saliva meets gastric acid. Nitric oxide generates N-nitrosative stress on reacting with oxygen at neutral pH. We aimed to ascertain if luminal nitric oxide exerts nitrosative stress
Pinar Erkekoglu et al.
Toxicology mechanisms and methods, 20(2), 45-52 (2010-01-27)
Nitrites are ubiquitous environmental contaminants present in drinking water and foods. Nitrosamines can be formed endogenously from nitrate and nitrite and secondary amines or may be present in food, tobacco smoke, and drinking water. The major goal of this work
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