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G5001

Sigma-Aldrich

DL-Glyceraldehyde

DL-Glyceraldehyde

≥90% (GC)

Synonym(s):

α,β-Dihydroxypropionaldehyde, 2,3-Dihydroxypropanal

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About This Item

Empirical Formula (Hill Notation):
C3H6O3
CAS Number:
Molecular Weight:
90.08
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25
Pricing and availability is not currently available.

biological source

synthetic

Quality Level

Assay

≥90% (GC)

form

powder

color

white to off-white

mp

145  °C ((293 °F ))

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

room temp

SMILES string

[H]C(=O)C(O)CO

InChI

1S/C3H6O3/c4-1-3(6)2-5/h1,3,5-6H,2H2

InChI key

MNQZXJOMYWMBOU-UHFFFAOYSA-N

General description

Glyceraldehyde is a simple monosaccharide.[1] Based on the number of carbon atoms and the type of carbonyl group present, glyceraldehyde belongs to subgroup triose. It is a colourless and sweet compound.[2]

Application

DL-Glyceraldehyde has been used:
  • as modifying reagent in the preparation of crystallization solution[3]
  • as a substrate to measure aldose reductase activity[4]
  • in the preparation of d/l-glyceraldehyde stock to determine the specific activity of GAPDH (glyceraldehyde 3-phosphate dehydrogenase)[5]

Biochem/physiol Actions

Glyceraldehyde serves as an efficient cross-linking agent and is considered non-toxic.[1] It is an intermediate of a number of metabolic such as glycolysis and pentose phosphate pathway.[2]

Other Notes

DL-Glyceraldehyde is a substrate for the enzyme aldose reductase.
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Raman and infrared spectroscopy of carbohydrates: a review
Wiercigroch E, et al.
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 185(5), 317-335 (2017)
Chethan Sampath et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 84, 502-513 (2016-09-30)
Hyperglycemic stress activates polyol pathway and aldose reductase (AR) key enzyme responsible for generating secondary complications during diabetes. In this study the therapeutic potential of phloretin, epigallocatechin 3-gallate (EGCG) and [6]-gingerol were evaluated for anti-glycating and AR inhibitory activity in
GAPDH and Intermediary Metabolism
GAPDH: Biological Properties and Diversity, 37-59 (2012)
René L Jacobs et al.
Molecular genetics and metabolism, 120(4), 325-336 (2017-03-16)
Classical homocystinuria (HCU) due to inactivating mutation of cystathionine β-synthase (CBS) is a poorly understood life-threatening inborn error of sulfur metabolism. A previously described cbs-/- mouse model exhibits a semi-lethal phenotype due to neonatal liver failure. The transgenic HO mouse
Kazuo Iwasa et al.
Journal of neuroimmunology, 301, 30-34 (2016-11-20)
Caveolin-3 is a muscle-specific membrane protein that localizes to the sarcolemma and T-tubule system. Caveolin-3 is needed for muscle repair and skeletal muscle development. The objective of this study was to compare caveolin-3 expression in myasthenia gravis (MG) and control

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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