A3139

Albumin from mouse serum

lyophilized powder, ≥96% (agarose gel electrophoresis)

• Synonym(s): Mouse albumin
• CAS Number: 9048-46-8
• EC Number: 232-936-2
• MDL number: MFCD00804573
• UNSPSC Code: 12352202
• NACRES: NA.27

Properties

• biological source: mouse
• Quality Level: 200
• Assay: ≥96% (agarose gel electrophoresis)
• form: lyophilized powder
• technique(s): ELISA: suitable; electrophoresis: suitable
• UniProt accession no.: P07724
• storage temp.: 2-8°C
• Gene Information: mouse ... ALB(11657)

Description

General description

Mouse albumin gene is mapped to mouse chromosome 5.[1] It codes for an albumin, which is the most prominent protein in the blood plasma.[2] Albumin is produced by the mature liver.[1] Mouse albumin gene promoter region includes minimum six binding sites (A to F) for specific DNA-binding proteins.[3]

Application

Albumin from mouse serum has been used in labelling by probe 2 for the characterization of matrix metalloprotease-12 by one-dimensional electrophoresis.[4] It has also been used for the preparation of calibrator and controls in enzyme-linked immunosorbent assay (ELISA).[5]

Biochem/physiol Actions

Albumin facilitates the formation of cytoplasmic lipid droplets in pancreatic stellate cells and adipocyte differentiation of 3T3-L1 cells. In addition, it effectively regulates biological activity of adipogenic transcription factors, peroxisome proliferator-activated receptor (PPAR - γ ) and (CCAAT/enhancer binding protein (C/EBP).[6]

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves