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Oxacillin sodium salt monohydrate

VETRANAL®, analytical standard

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About This Item

Linear Formula:
C19H18N3O5SNa · H2O
CAS Number:
Molecular Weight:
441.43
Beilstein:
4287093
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Agency

EPA 1694

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

[Na+].[H]O[H].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)c3c(C)onc3-c4ccccc4)C([O-])=O

InChI

1S/C19H19N3O5S.Na.H2O/c1-9-11(12(21-27-9)10-7-5-4-6-8-10)15(23)20-13-16(24)22-14(18(25)26)19(2,3)28-17(13)22;;/h4-8,13-14,17H,1-3H3,(H,20,23)(H,25,26);;1H2/q;+1;/p-1/t13-,14+,17-;;/m1../s1

InChI key

ZVIYWUUZWWBNMB-VICXVTCVSA-M

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General description

Chemical structure: ß-lactam
Oxacillin is a bactericidal agent, which can be used for the treatment of infections due to penicillinase-producing staphylococci. Its mode of action involves inhibition of bacterial cell wall synthesis and thus affects bacterial penicillin-binding proteins.

Application

Oxacillin sodium salt monohydrate has been used as a reference standard in the determination of the analyte in milk samples by receptor-binding assay test.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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CRC Desk Reference of Clinical Pharmacology (1997)
Detection of antibiotics in sheep milk by receptor-binding assays.
Beltran CM, et al.
International dairy journal, 34(2), 184-189 (2014)
Bintao Cui et al.
Journal of clinical microbiology, 51(1), 9-14 (2012-10-12)
Coagulase-negative staphylococci have been identified as major causes of late-onset neonatal bacteremia in neonatal intensive care units. Sixty isolates of Staphylococcus capitis obtained from blood cultures of neonates between 2000 and 2005 were examined in this study. Biochemical analysis confirmed
Claire Nonhoff et al.
Journal of clinical microbiology, 50(10), 3359-3360 (2012-07-21)
We evaluated the performance of a new immunochromatographic assay (ICA), the Clearview Exact PBP2a, for rapid detection of penicillin-binding protein 2a (PBP2a) in a challenge set of Staphylococcus aureus strains showing MICs to oxacillin of ≤16 mg/liter. The sensitivity and
Nur Salwani Bakar et al.
Pakistan journal of pharmaceutical sciences, 25(3), 633-638 (2012-06-21)
This study evaluated in vitro activity of 9 flavonoids in combination with vancomycin or oxacillin against vancomycin-intermediate Staphylococcus aureus (VISA) ATCC 700699 by employing the checkerboard method to obtain Minimal inhibitory concentration (MIC) and fractional inhibitory concentration (FIC) index. Six

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