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Sigma-Aldrich

Hyamine® 1622 solution

4 mM in H2O

Synonym(s):

(Diisobutylphenoxyethoxyethyl)dimethylbenzylammonium chloride solution

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About This Item

CAS Number:
Beilstein:
3898548
MDL number:
UNSPSC Code:
12352112
PubChem Substance ID:
NACRES:
NA.22
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Quality Level

concentration

4 mM in H2O

density

0.998 g/mL at 20 °C

SMILES string

[Cl-].CC(C)(C)CC(C)(C)c1ccc(OCCOCC[N+](C)(C)Cc2ccccc2)cc1

InChI

1S/C27H42NO2.ClH/c1-26(2,3)22-27(4,5)24-13-15-25(16-14-24)30-20-19-29-18-17-28(6,7)21-23-11-9-8-10-12-23;/h8-16H,17-22H2,1-7H3;1H/q+1;/p-1

InChI key

UREZNYTWGJKWBI-UHFFFAOYSA-M

General description

Hyamine® 1622 is a cationic detergent benzethonium chloride.[1] Poly(vinyl chloride) membrane ion-selective electrode for the Hyamine 1622 cation has been proposed.[2] Its sorption on soil surfaces has been investigated.[3] It is widely used in cosmetics and shampoos due to its antimicrobial and cationic surfactant properties.[4]

Application

Hyamine® 1622 solution was used as surfactant to examine its acute toxicity and effect on oxidative stress and cholinesterase (ChE) activity in Dugesia japonica.[4] It may be employed as stopping reagent in the improved Eliman procedure for erythrocyte cholinesterase.[1]

Legal Information

Hyamine is a registered trademark of Lonza Group Ltd.

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 3

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Mei-Hui Li
Chemosphere, 70(10), 1796-1803 (2007-10-02)
Eight widely used surfactants (cetyltrimethylammonium bromide; CTAB, benzethonium chloride; Hyamine 1622, 4-nonylphenol; NP, octylphenol ethoxylate; Triton X-100, dodecylbenzene sulfonate; LAS, lauryl sulfate; SDS, pentadecafluorooctanoic acid; PFOA, and perfluorooctane sulfonate; PFOS) were selected to examine their acute toxicities and effects on
Poly (vinyl chloride) containing dibenzo-18-crown-6 as an ion-selective membrane for hyamine 1622.
Khalil MM, et al.
Analytical Letters, 19(7-8), 807-824 (1986)
Sorption of anionic surfactants SDS, AOT and cationic surfactant Hyamine 1622 on natural soils.
Atay N, et al.
Water, Air, Soil Pollut., 136(1-4), 55-68 (2002)
P M George et al.
Clinical chemistry, 29(2), 365-368 (1983-02-01)
The procedure of Dietz et al. (Clin. Chem. 19: 1309-1313, 1973) for plasma cholinesterase (EC 3.1.1.7) gives a background absorbance of 1.4 A when extended to erythrocyte cholinesterase (EC 3.1.1.8) measurement, because the peak absorbance of the reaction product, 5-thionitrobenzoate
Naoto Kojima et al.
Bioorganic & medicinal chemistry letters, 18(24), 6451-6453 (2008-11-11)
C4-Fluorinated analogues of solamin, an antitumor acetogenin, were synthesized and investigated for their antitumor activities against 39 tumor cell lines. C4-Fluorinated solamins showed more potent growth inhibitory activity against cancer cell lines than solamin.

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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