47638

Fmoc-Val-OH

≥98.0% (HPLC)

• Synonym(s): N-(9-Fluorenylmethoxycarbonyl)-L-valine, Fmoc-L-valine
• Empirical Formula (Hill Notation): C₂₀H₂₁NO₄
• CAS Number: 68858-20-8
• Molecular Weight: 339.39
• Beilstein: 2177443
• EC Number: 272-515-0
• MDL number: MFCD00037124
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57651055
• NACRES: NA.26

Properties

• Assay: ≥98.0% (HPLC)
• form: solid
• optical activity: [α]20/D −17±1°, c = 1% in DMF
• reaction suitability: reaction type: C-H Activation; reaction type: Fmoc solid-phase peptide synthesis; reagent type: ligand; reaction type: Peptide Synthesis
• mp: 143-145 °C (lit.); 143-147 °C
• application(s): peptide synthesis
• functional group: Fmoc; amine; carboxylic acid
• storage temp.: 2-8°C
• SMILES string: CC(C)[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
• InChI: 1S/C20H21NO4/c1-12(2)18(19(22)23)21-20(24)25-11-17-15-9-5-3-7-13(15)14-8-4-6-10-16(14)17/h3-10,12,17-18H,11H2,1-2H3,(H,21,24)(H,22,23)/t18-/m0/s1
• InChI key: UGNIYGNGCNXHTR-SFHVURJKSA-N

Description

General description

Fmoc-Val-OH also known as Fmoc-L-valine, is a versatile reagent used in the Fmoc Solid-phase peptide synthesis.

Application

Fmoc-Val-OH can be used as a starting material to synthesize:

• difficult sequence-containing pentapeptides using O-acyl isodipeptide unit
• peptides by backbone amide linker (BAL) strategy via Fmoc Solid-phase synthesis

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves