226084

(Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate

97%, for peptide synthesis

• Synonym(s): BOP, BOP Reagent, Castros reagent
• Empirical Formula (Hill Notation): C₁₂H₂₂F₆N₆OP₂
• CAS Number: 56602-33-6
• Molecular Weight: 442.28
• Beilstein: 4287025
• EC Number: 260-279-1
• MDL number: MFCD00011948
• UNSPSC Code: 12352107
• PubChem Substance ID: 24853542
• NACRES: NA.22

Properties

• Product Name: (Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate, 97%
• Quality Level: 200
• Assay: 97%
• form: powder
• reaction suitability: reaction type: Coupling Reactions
• mp: >130 °C (dec.) (lit.)
• application(s): peptide synthesis
• functional group: amine
• storage temp.: 2-8°C
• SMILES string: F[P-](F)(F)(F)(F)F.CN(C)[P+](On1nnc2ccccc12)(N(C)C)N(C)C
• InChI: 1S/C12H22N6OP.F6P/c1-15(2)20(16(3)4,17(5)6)19-18-12-10-8-7-9-11(12)13-14-18;1-7(2,3,4,5)6/h7-10H,1-6H3;/q+1;-1
• InChI key: MGEVGECQZUIPSV-UHFFFAOYSA-N

Description

Application

Reagent for:
Peptide coupling[1]
Synthesis of esters[2]
Esterification of carboxylic acids[3][4]
Plasmid CAN-encapsulating liposomes[5]
Synthesis of magnolamide for antioxidative activity[6]

Catalyst for preparation of 9-acridinecaroboxamide derivative[7]

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H228,H315,H335
• Precautionary Statements: P210 - P240 - P241 - P261 - P264 - P302 + P352
• Hazard Classifications: Flam. Sol. 1 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Supplementary Hazards: EUH044
• Storage Class Code: 4.1A - Other explosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves