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Key Documents

217719

Sigma-Aldrich

4-Amino-2-chlorobenzoic acid

97%

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About This Item

Linear Formula:
H2NC6H3(Cl)CO2H
CAS Number:
Molecular Weight:
171.58
Beilstein:
2803668
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

reaction suitability

reaction type: solution phase peptide synthesis

mp

211 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

Nc1ccc(C(O)=O)c(Cl)c1

InChI

1S/C7H6ClNO2/c8-6-3-4(9)1-2-5(6)7(10)11/h1-3H,9H2,(H,10,11)

InChI key

MBDUKNCPOPMRJQ-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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R R Weiss et al.
Anesthesia and analgesia, 62(2), 168-173 (1983-02-01)
2-Chloroprocaine (CP) has recently been recommended as a less toxic alternative to amide-type local anesthetics due to its rapid metabolism. A double-blind, randomized study comparing CP to lidocaine when used for paracervical block was carried out. Twenty-nine patients received CP
B R Kuhnert et al.
Anesthesia and analgesia, 62(12), 1089-1094 (1983-12-01)
Little is known about the pharmacology of the metabolites of 2-chloroprocaine in obstetrical patients. The primary objective of this study was to describe the elimination of 2-chloroaminobenzoic acid (CABA) in maternal and neonatal urine after epidural anesthesia. A secondary objective
E H Philipson et al.
American journal of obstetrics and gynecology, 151(3), 322-324 (1985-02-01)
Amide-linked local anesthetic agents, such as lidocaine and bupivacaine, can become "trapped" in their ionized forms on the fetal side of the placenta, and therefore their net transfer across the placenta is increased. An ester-linked local anesthetic agent, 2-chloroprocaine, is
G Menon et al.
Journal of pharmaceutical sciences, 73(2), 251-253 (1984-02-01)
A high-performance liquid chromatographic method has been developed for the simultaneous determination of chloroprocaine hydrochloride and its hydrolytic degradation product, 4-amino-2-chlorobenzoic acid. Separation is achieved using a mu-Bondapak C18 column and the eluant, water-acetonitrile-methanol-glacial acetic acid (74:20:5:1) containing 0.05-0.08% (w/v)
F Brun et al.
Journal of pharmaceutical and biomedical analysis, 14(8-10), 1251-1259 (1996-06-01)
The separation of HPLC of basic drugs on silica-based reversed phases remains a major problem because of the interaction between the residual silanol groups of the silica and the amino function of the drug. This paper describes the validation of

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