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Key Documents

SAB4300082

Sigma-Aldrich

Anti-phospho-PLCG1 (pTyr783) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-PLC-II antibody produced in rabbit, Anti-PLC1 antibody produced in rabbit, Anti-PLC148 antibody produced in rabbit, Anti-PLCgamma1 antibody produced in rabbit, Anti-phospholipase C, gamma 1 antibody produced in rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~155 kDa

species reactivity

human, rat, mouse

concentration

1 mg/mL

technique(s)

western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(G-F-YP-V-E)

NCBI accession no.

NP_002651.2

UniProt accession no.

P19174

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr783)

Gene Information

human ... PLCG1(5335)

Immunogen

Peptide sequence around phosphorylation site of tyrosine 783 (G-F-Y(p)-V-E), according to the protein PLCG1.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Target description

PLC-gamma is a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Stephanie M Muscat et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 43(1), 155-172 (2022-11-18)
Perioperative neurocognitive disorders (PNDs) are characterized by confusion, difficulty with executive function, and episodic memory impairment in the hours to months following a surgical procedure. Postoperative cognitive dysfunction (POCD) represents such impairments that last beyond 30 d postsurgery and is
Katrin Hipke et al.
Frontiers in cell and developmental biology, 11, 1169962-1169962 (2023-06-29)
Aggregation of the Tar DNA-binding protein of 43 kDa (TDP-43) is a pathological hallmark of amyotrophic lateral sclerosis and frontotemporal dementia and likely contributes to disease by loss of nuclear function. Analysis of TDP-43 function in knockout zebrafish identified an endothelial

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