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RAB0412

Sigma-Aldrich

PTH / Parathyroid Hormone EIA Kit

for serum, plasma, culture supernatant and cell lysates

Synonym(s):

PTH, Parathyroid hormone, PTH1, Parathormone, Parathyrin

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

rat, human, mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
enzyme immunoassay: suitable

input

sample type plasma
sample type cell lysate
sample type serum
sample type culture supernatant(s)

assay range

inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 1.27 pg/mL
standard curve range: 1-1000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... PTH(5741)

Related Categories

General description

The PTH Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting PTH peptide based on the principle of Competitive Enzyme Immunoassay.

Immunogen

Parathyroid Hormone (PTH), synthetic peptide

Application

PTH / arathyroid hormone EIA kit has been used to determine parathyroid hormone (PTH) levels in human embryonic kidney (HEK293) cells.

Biochem/physiol Actions

Parathyroid hormone (PTH) plays a vital role in regulation calcium homeostasis. It increases bone mass in animals and humans by inhibiting osteoblast apoptosis. PTH has potential applications in preventing fractures in postmenopausal women with osteoporosis. Irregular diurnal patterns of PTH leads to sustained mild hypercalcemia in non dialyzed chronic kidney disease (CKD) patients. PTH, along with other heart failure biomarkers play a vital role in measuring disease severity and prognosis of heart failure with preserved ejection fraction (HFpEF). Variation in PTH leads to osteoporosis in asymptomatic hyperparathyroidism (HPT).

Kit Components Also Available Separately

Product No.
Description
SDS

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Parathyroid hormone is associated with heart failure with preserved ejection fraction.
Bezgin T
Bratislavske lekarske Listy null
Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormone.
Jilka R L
The Journal of Clinical Investigation null
Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis.
Neer RM
The New England Journal of Medicine null
Parathyroid Hormone Polymorphism RS6254 is Associated with the Development and Severity of Osteoporosis in Asymptomatic but not Normocalcemic Hyperthyroidism.
Diaz-Soto G
Hormone and Metabolic Research null
Abnormal Diurnal Patterns of Parathyroid Hormone are Associated with Sustained Mild Hypercalcemia in Non-Dialyzed Chronic Kidney Disease.
Yamato M
Clinical Laboratory null
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