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46080

Sigma-Aldrich

Ethyl cellulose

48.0-49.5% (w/w) ethoxyl basis

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About This Item

CAS Number:
9004-57-3
MDL number:
MFCD00131037
UNSPSC Code:
12352201
NACRES:
NA.25

Quality Level

200

Assay

48.0-49.5% (w/w) (ethoxyl)

form

coarse powder
powder

autoignition temp.

698 °F

color

beige

refractive index

n20/D 1.47 (lit.)

viscosity

30-70 mPa.s, 5 % in toluene/ethanol 80:20(25 °C)

density

1.14 g/mL at 25 °C (lit.)

SMILES string

O1[C@H](C(C(C(C1COCC)OCC)OCC)OCC)O[C@@H]2C(OC(C(C2OCC)OCC)OCC)COCC

InChI

1S/C28H54O11/c1-9-29-17-19-21(31-11-3)23(32-12-4)26(35-15-7)28(38-19)39-22-20(18-30-10-2)37-27(36-16-8)25(34-14-6)24(22)33-13-5/h19-28H,9-18H2,1-8H3/t19?,20?,21?,22-,23?,24?,25?,26?,27?,28+/m1/s1

InChI key

MINRZDZESGXKDM-OLIDUAMRSA-N

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Application

Ethyl cellulose is generated by converting a variable number of hydroxyl groups on the repeating glucose units to ethyl ether groups. Ethylcellulose is used in the preparation of biostructures such as matrices, microspheres, microparticles, pellets and tablets for use in drug delivery.

Preparation Note

Ethyl Cellulose is soluble in a wide range of solvents such as aliphatic alcohols, chlorinated solvents, and natural oils. It is insoluble in water, glycerin, and prolylene glycol.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL7181
BCCM2923
BCCK5333
BCCH0473
BCCJ0430

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Biological & pharmaceutical bulletin, 35(11), 1926-1931 (2012-11-06)
Production of drug nanoparticles is an effective strategy to enhance solubility and oral absorption of water-insoluble drugs. The handling of drug nanoparticles has been an important issue in drug formulation because nanoparticles easily aggregate each other and redispersion of these
H V Adikane et al.
Applied biochemistry and biotechnology, 169(3), 1026-1038 (2013-01-09)
The chemical modification of developed ethyl cellulose-based membrane was carried out to make it suitable for bioseparation. The different reagents were used for the modification of membrane to couple protein A (PA) to study the purification of immunoglobulin G (IgG)
Ritesh M Pabari et al.
Expert opinion on drug delivery, 9(12), 1463-1474 (2012-10-16)
To examine the potential of a novel 3-fluid nozzle spray drying technology to formulate differentiated layered microparticles (MPs) of diclofenac sodium (DFS)/ethyl cellulose (EC). DFS/EC MPs were formulated using the inner and/or outer nozzles of a novel 3-fluid nozzle and
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