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217247

Sigma-Aldrich

Sodium thiosulfate pentahydrate

ACS reagent, ≥99.5%

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About This Item

Linear Formula:
Na2S2O3 · 5H2O
CAS Number:
Molecular Weight:
248.18
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent

Quality Level

Agency

suitable for EPA 1621
suitable for ISO 25101
suitable for SM 2310
suitable for SM 2320
suitable for SM 4500 - NH3

Assay

≥99.5%

form

crystalline powder
crystals
pellets

impurities

≤0.002% N compounds
≤0.005% insolubles

pH

6.0-8.4 (25 °C, 5%)

solubility

water: soluble(lit.)

anion traces

S2-: passes test
SO42- and SO32-: ≤0.1%

cation traces

N: ≤0.002%

SMILES string

O.O.O.O.O.[Na+].[Na+].[O-]S([O-])(=O)=S

InChI

1S/2Na.H2O3S2.5H2O/c;;1-5(2,3)4;;;;;/h;;(H2,1,2,3,4);5*1H2/q2*+1;;;;;;/p-2

InChI key

PODWXQQNRWNDGD-UHFFFAOYSA-L

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General description

Sodium thiosulfate pentahydrate is a hydrated form of sodium thiosulfate. It is used as a sulfur source for the preparation of various organosulfur compounds.

Application

Applied in a widely useful, thiosulfate-assisted, synthesis of a variety of diamine-CuCN complexes.
Sodium thiosulfate pentahydrate can be used as a sulfur source to synthesize:      
  • Thioester derivatives via one-pot two-step reactions with organic halides and aryl anhydrides.      
  • Sulfur nanoparticles using F. benghalensis leaf extract which acts as a reducing and capping agent.      
  • Unsymmetrical heteroaryl thioethers via multicomponent reaction with heteroaryl chlorides and alcohols.

It can also be used in the fabrication of microencapsulated phase change materials for thermal energy storage applications.

Features and Benefits

Na2S2O3 5H2O is a low toxic and odorless reagent that can be easily used in large-scale operations.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sodium thiosulfate pentahydrate: a redetermination by neutron diffraction.
Lisensky GC and Levy HA.
Acta Crystallographica Section B, Structural Science, Crystal Engineering and Materials, 34(6), 1975-1977 (1978)
Fingerprint imaging by scanning electrochemical microscopy.
Zhang M and Girault HH.
Electrochemical Communications, 9(7), 1778-1782 (2007)
Fred B. Stocker et al.
Inorganic chemistry, 38(5), 984-991 (2001-10-24)
A new synthetic procedure developed recently in our laboratories has made possible the synthesis of variety of new complexes of CuCN with diamines. Synthesis was effected by adding the ligand to a solution of CuCN in aqueous sodium thiosulfate. This
Nuclear magnetic resonance in sodium thiosulfate pentahydrate.
Murty CRK and El Saffar ZM.
Acta Crystallographica, 15(6), 536-538 (1962)
Melani Sooriyaarachchi et al.
Metallomics : integrated biometal science, 5(3), 197-207 (2013-02-28)
Cis-Platin (CP) is a remarkably effective Pt-based anticancer drug, but it also exhibits severe toxic side-effects, including nephrotoxicity and ototoxicity. Previous studies conducted with mammalian model organisms have clearly demonstrated that the intravenous administration of N-acetyl-L-cysteine (NAC) or sodium thiosulfate

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