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Supelco

Cefalonium hydrate

VETRANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C20H18N4O5S2 · xH2O
CAS Number:
Molecular Weight:
458.51 (anhydrous basis)
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

O.NC(=O)c1cc[n+](CC2=C(N3[C@H](SC2)[C@H](NC(=O)Cc4cccs4)C3=O)C([O-])=O)cc1

InChI

1S/C20H18N4O5S2.H2O/c21-17(26)11-3-5-23(6-4-11)9-12-10-31-19-15(18(27)24(19)16(12)20(28)29)22-14(25)8-13-2-1-7-30-13;/h1-7,15,19H,8-10H2,(H3-,21,22,25,26,28,29);1H2/t15-,19-;/m1./s1

InChI key

GVIOXNHDFXYYMP-AEFICSSHSA-N

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General description

Cefalonium is a cephalosporin antibiotic which belongs to the β-lactam class, used in both human and veterinary medicine. Its mode of action involves inhibiting of enzymes involved in the biosynthesis of cell wall peptidoglycan resulting in the lysis of bacteria.
Chemical structure: ß-lactam

Application

Cefalonium hydrate may be used for the determination of cefalonium in bovine muscle by liquid chromatography coupled to tandem mass spectrometry.
Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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[Antibacterial activity of beta-lactam antibiotics in freshly-collected bovine dry udder secretions].
B Marx et al.
Berliner und Munchener tierarztliche Wochenschrift, 92(22), 437-440 (1979-11-15)
[Effect of and length of protection offered by Cepravin Dry Cow in the prevention of summer-mastitis (author's transl)].
J Sol et al.
Tijdschrift voor diergeneeskunde, 107(12), 466-474 (1982-06-15)
A J Bradley et al.
Journal of dairy science, 93(4), 1566-1577 (2010-03-27)
The dry period is a critical time in the lactation cycle, being the optimum time to cure existing intramammary infection (IMI) as well as encompassing the periods of highest susceptibility to new infection. Currently, IMI in the dry period is
G Ziv et al.
The Veterinary quarterly, 3(2), 74-79 (1981-04-15)
The comparative efficacy of a product containing 500 mg benzathine cloxacillin (Orbenin D.C.). another product containing 100 mg nafcillin, 300 mg procaine benzylpenicillin and 100 mg dihydrostreptomycin (Nafpenzal D.C.) and a third product containing 250 mg cephalonium (Cepravin D.C.), in
S McDougall
New Zealand veterinary journal, 58(1), 45-58 (2010-03-05)
To test the non-inferiority of a novel cephalonium formulation of antibiotic dry-cow therapy (DCT) to a reference formulation, infused at the end of lactation, for cure of existing and prevention of new intramammary infections (IMI). Cows with a maximum somatic

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