233279

Coagulation Factor IX, Human Plasma

Coagulation Factor IX, Human Plasma, CAS 9001-28-9, is a native coagulation factor IX from human plasma. Sold on the basis of plasma equivalent units. 100 plasma equivalent units = 500 µg.

• Synonym(s): Coagulation Factor IX, Human Plasma, Antihemophilic Factor B, Christmas Factor, Plasma Thromboplastin Component, PTC
• CAS Number: 9001-28-9
• MDL number: MFCD00163303
• UNSPSC Code: 12352202
• NACRES: NA.25

Properties

• biological source: human plasma
• Quality Level: 200
• description: Merck USA index - 14, 3922
• Assay: ≥95% (SDS-PAGE)
• form: liquid
• specific activity: ≥150 units/mg protein (clotting assay)
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; avoid repeated freeze/thaw cycles
• shipped in: wet ice
• storage temp.: −70°C

Description

General description

Native coagulation factor IX from human plasma. Sold on the basis of plasma equivalent units. 100 plasma equivalent units are equal to 500 µg of Factor IX. In vivo, activation of Factor IX to IXa occurs via either the tissue factor/Factor VIIa complex (the extrinsic pathway), or Factor XIa (the intrinsic pathway). Activated Factor IXa, in a complex with Factor VIIIa, can then convert Factor X to Xa, the catalytic component of the prothrombinase complex.

Native coagulation factor IX from human plasma. Sold on the basis of plasma equivalent units. 100 plasma equivalent units are equal to 500 µg of Factor IX. In vivo, activation of Factor IX to IXa occurs via either the tissue factor/Factor VIIa complex (the extrinsic pathway), or Factor XIa (the intrinsic pathway). Activated Factor IXa, in a complex with Factor VIIa, can then convert Factor X to Xa, the catalytic component of the prothrombinase complex.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In 100 mM NaCl, 20 mM Tris-HCl, 1 mM benzamidine, pH 7.5.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Analysis Note

Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable