850345C

14:0 PC (DMPC)

1,2-dimyristoyl-sn-glycero-3-phosphocholine, chloroform

• Synonym(s): 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine; DMPC; PC(14:0/14:0)
• Empirical Formula (Hill Notation): C₃₆H₇₂NO₈P
• CAS Number: 18194-24-6
• Molecular Weight: 677.93
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 2.5 mL (850345C-25mg); pkg of 1 × 20 mL (850345C-500mg); pkg of 2 × 20 mL (850345C-1g); pkg of 2 × 4 mL (850345C-200mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 850345C
• concentration: 10 mg/mL (850345C-25mg); 25 mg/mL (850345C-1g); 25 mg/mL (850345C-200mg); 25 mg/mL (850345C-500mg)
• lipid type: phospholipids; cardiolipins
• shipped in: dry ice
• storage temp.: −20°C
• InChI: 1S/C36H72NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-35(38)42-32-34(33-44-46(40,41)43-31-30-37(3,4)5)45-36(39)29-27-25-23-21-19-17-15-13-11-9-7-2/h34H,6-33H2,1-5H3/t34-/m0/s1
• InChI key: CITHEXJVPOWHKC-UMSFTDKQSA-N

Description

General description

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

14:0 PC (DMPC) has been used in liposome preparation. It is also suitable for use:

• in the preparation of lipid bicelles for nuclear magnetic resonance (NMR) experiments
• in labeled vesicle preparation for fluorescence polarization measurements
• as internal standard (IS) for the quantitation of phosphatidylcholine (PC) by liquid chromatography with tandem mass spectrometry (LC-MS-MS)

Biochem/physiol Actions

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850345C-1g)

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850345C-500mg)

5 mL Clear Glass Sealed Ampule (850345C-200mg)

5 mL Clear Glass Sealed Ampule (850345C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Precautionary Statements: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Target Organs: Central nervous system, Liver,Kidney
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point(F): does not flash
• Flash Point(C): does not flash