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Sigma-Aldrich

Diphenyl ditelluride

98%

Synonym(s):

Phenyl ditelluride

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About This Item

Linear Formula:
(C6H5)2Te2
CAS Number:
32294-60-3
Molecular Weight:
409.41
EC Number:
250-982-1
MDL number:
MFCD00192106
UNSPSC Code:
12352100
PubChem Substance ID:
24863651
NACRES:
NA.22

Quality Level

100

Assay

98%

form

powder

mp

65-67 °C (lit.)

SMILES string

[Te]([Te]c1ccccc1)c2ccccc2

InChI

1S/C12H10Te2/c1-3-7-11(8-4-1)13-14-12-9-5-2-6-10-12/h1-10H

InChI key

VRLFOXMNTSYGMX-UHFFFAOYSA-N

Related Categories

General description

Diphenyl ditelluride (PhTe)2 is a versatile reagent used in the organic synthesis. Neurotoxicity by (PhTe)2 depends on the modulation of signaling pathways initiated at the plasma membrane. Comparative toxicological effects of diphenyl diselenide and (PhTe)2 in mice after in vivo administration has been reported. Teratogenic effects of (PhTe)2 on chicken embryo development has been investigated. The oxidative addition of (PhTe)2 to [Pd(PPh3)4] in dichloromethane is reported to yield [Pd6Cl2Te4(TePh)2(PPh3)6]·1/2CH2Cl2.

Application

Diphenyl ditelluride may be used in the assay of organolithium and Grignard reagents.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Bruna Comparsi et al.
Toxicology mechanisms and methods, 24(8), 529-535 (2014-05-28)
Diphenyl ditelluride (PhTe)₂ is a versatile molecule used in the organic synthesis and it is a potential prototype for the development of novel biologically active molecules. The mechanism(s) involved in (PhTe)₂ toxicity is(are) elusive, but thiol oxidation of critical proteins
Hamit Celik et al.
Neurotoxicology, 80, 29-40 (2020-06-17)
The fact that oxaliplatin (OXL), a platinum-based chemotherapeutic drug, causes severe neuropathy greatly limits its clinical use. This study investigated the effects of lycopene, a potent antioxidant, on OXL-induced central and peripheral neuropathy. In this study, 30 min after oral administration
Regina Pessoa-Pureur et al.
Oxidative medicine and cellular longevity, 2014, 458601-458601 (2014-07-23)
Evidence from our group supports that diphenyl ditelluride (PhTe)2 neurotoxicity depends on modulation of signaling pathways initiated at the plasma membrane. The (PhTe)2-evoked signal is transduced downstream of voltage-dependent Ca(2+) channels (VDCC), N-methyl-D-aspartate receptors (NMDA), or metabotropic glutamate receptors activation
Robert B Cody et al.
Journal of the American Society for Mass Spectrometry, 30(7), 1321-1324 (2019-05-08)
Elemental compositions are commonly determined from the exact m/z of the monoisotopic peak, which is often the lightest isotope. However, the lightest isotope peak is often weak or absent and the monoisotopic peak can be difficult to identify for organometallics
Daiane Francine Meinerz et al.
PeerJ, 2, e290-e290 (2014-04-09)
Organoselenium compounds have been pointed out as therapeutic agents. In contrast, the potential therapeutic aspects of tellurides have not yet been demonstrated. The present study evaluated the comparative toxicological effects of diphenyl diselenide (PhSe)2 and diphenyl ditelluride (PhTe)2 in mice
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