138576

1-Adamantylamine

97%

• Synonym(s): 1-Aminoadamantane
• Empirical Formula (Hill Notation): C₁₀H₁₇N
• CAS Number: 768-94-5
• Molecular Weight: 151.25
• Beilstein: 2204333
• EC Number: 212-201-2
• MDL number: MFCD00074732
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848359
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 97%
• mp: 206-208 °C (lit.)
• solubility: 1 M HCl: soluble 5%, clear to hazy, colorless to faint yellow or tan
• SMILES string: NC12C[C@H]3C[C@H](C[C@H](C3)C1)C2
• InChI: 1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2/t7-,8+,9-,10-
• InChI key: DKNWSYNQZKUICI-CHIWXEEVSA-N
• Gene Information: human ... GRIN2A(2903)

Description

General description

1-Adamantylamine, also known as Amantadine, is an adamantane derivative where an amino group is replaced by one of the methyl groups of adamantane. It is commonly used as a starting material in various organic reaction, such as monomer synthesis and one-pot synthesis of 1-adamantylhydrazine.

Application

1-Adamantylaminecan be used as a reactant to synthesize:

• Adamantyl ureas by reacting with isocyanates in the presence of triethylamine.
• N-(1-adamantyl)-2-chloroacetamide from chloroacetyl chloride in the presence of potassium carbonate.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves