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C1426

Sigma-Aldrich

Cesium methanesulfonate

used in patch clamp techniques

Synonym(s):

CsMSF, CsMeS, Methanesulfonic acid cesium salt

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About This Item

Linear Formula:
CH3O3SCs
CAS Number:
2550-61-0
Molecular Weight:
228.00
MDL number:
MFCD00075523
UNSPSC Code:
12161700
PubChem Substance ID:
24892412
NACRES:
NA.25

Quality Level

100

form

powder

mp

262-264 °C (lit.)

SMILES string

[Cs+].CS([O-])(=O)=O

InChI

1S/CH4O3S.Cs/c1-5(2,3)4;/h1H3,(H,2,3,4);/q;+1/p-1

InChI key

DJKJXRLREATOMF-UHFFFAOYSA-M

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General description

Cesium methanesulfonate is used as a component of intracellular recording solutions of electrodes for patch clamp techniques in cell electrophysiology studies. Cesium methanesulfonate is used as an current carrier as cesium acts as a potassium (K+) channel blocker, while methanesulfonate is not transported through chloride (Cl-) channels.

Application

Cesium methanesulfonate has been used as a supplement in intracellular solution for the patch clamp recording system.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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L Zhang et al.
Pflugers Archiv : European journal of physiology, 426(3-4), 247-253 (1994-02-01)
Using the whole-cell recording technique, we have examined the slow Ca(2+)-activated afterhyperpolarization (AHP) and its underlying current (IAHP) in hippocampal CA1 neurones of brain slices obtained from mature rats. Specifically we have studied the effects of the anion component of
Diverse voltage-sensitive dyes modulate GABAA receptor function.
Mennerick., S., et al.
The Journal of Neuroscience, 24, 2871-2879 (2010)
An optogenetics- and imaging-assisted simultaneous multiple patch-clamp recording system for decoding complex neural circuits.
Wang G
Nature Protocols, 10, 397-397 (2015)
P L Li et al.
American journal of physiology. Heart and circulatory physiology, 280(1), H208-H215 (2000-12-21)
The present study was designed to test the hypothesis that cADP-ribose (cADPR) increases Ca(2+) release through activation of ryanodine receptors (RYR) on the sarcoplasmic reticulum (SR) in coronary arterial smooth muscle cells (CASMCs). We reconstituted RYR from the SR of
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