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08657

Sigma-Aldrich

7-Amino-1,3-naphthalenedisulfonic acid monopotassium salt monohydrate

BioReagent, suitable for fluorescence, ≥98.0% (T)

Synonym(s):

2-Naphthylamine-6,8-disulfonic acid monopotassium salt, mono-Potassium 7-amino-1,3-naphthalenedisulfonate monohydrate, AGA

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About This Item

Empirical Formula (Hill Notation):
C10H8KNO6S2 · H2O
CAS Number:
303137-06-6
Molecular Weight:
359.42
Beilstein:
4835047
MDL number:
MFCD00287288
UNSPSC Code:
12352106
PubChem Substance ID:
329748623
NACRES:
NA.32

product line

BioReagent

Assay

≥98.0% (T)

solubility

H2O: soluble

fluorescence

λex 310 nm; λem 450 nm in 0.1 M phosphate pH 7.0

suitability

suitable for fluorescence

SMILES string

O.[K+].Nc1ccc2cc(cc(c2c1)S(O)(=O)=O)S([O-])(=O)=O

InChI

1S/C10H9NO6S2.K.H2O/c11-7-2-1-6-3-8(18(12,13)14)5-10(9(6)4-7)19(15,16)17;;/h1-5H,11H2,(H,12,13,14)(H,15,16,17);;1H2/q;+1;/p-1

InChI key

SHURQDDWGCOLFA-UHFFFAOYSA-M

Application

To label carbohydrates, this fluorescent reagent reacts with the reducing termini of oligosaccharids to form a Schiffs base, which can then be stabilized by reducing it with sodium cyanoborohydride.

Other Notes

Fluorescent label for carbohydrates

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Analysis of fluorescently labeled oligosaccharides by capillary electrophoresis and eletrospray ionization mass spectroscopy
Wolff, M. W., et al.
Biotechnol. Tech., 13, 797-797 (1999)
K B Lee et al.
Analytical biochemistry, 205(1), 108-114 (1992-08-15)
Polyacrylamide gel electrophoresis (PAGE) and capillary zone electrophoresis (CZE) were used to measure the activity of glycosyltransferases. Acceptor molecules were prepared by reductive amination of the monopotassium 7-amino-1,3-naphthalenedisulfonic acid (AGA) Schiff base with sugars. The resulting sugar conjugates were purified
Mingyan Hei et al.
American journal of perinatology, 32(8), 725-732 (2014-12-24)
This study aimed to compare the outcomes for symmetrical (sSGA) versus asymmetrical (aSGA) small for gestational age (SGA) < 32 weeks preterm infants. A total of 12,179 eligible infants admitted to the Canadian tertiary neonatal intensive care units (NICUs) over a 7-year-period
David R Holmes et al.
Journal of the American College of Cardiology, 65(24), 2614-2623 (2015-06-20)
The risk-benefit ratio of left atrial appendage closure (LAAC) versus systemic therapy (warfarin) for prevention of stroke, systemic embolism, and cardiovascular death in nonvalvular atrial fibrillation (NVAF) requires continued evaluation. This study sought to assess composite data regarding left atrial
Ben J Evans et al.
Cytogenetic and genome research, 145(3-4), 243-252 (2015-06-13)
Genome duplication creates redundancy in proteins and their interaction networks, and subsequent smaller-scale gene duplication can further amplify genetic redundancy. Mutations then lead to the loss, maintenance or functional divergence of duplicated genes. Genome duplication occurred many times in African
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