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P9755

Sigma-Aldrich

Pyridoxine hydrochloride

≥98% (HPLC)

Synonym(s):

Pyridoxine HCl, Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B6 hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C8H11NO3 · HCl
CAS Number:
58-56-0
Molecular Weight:
205.64
Beilstein:
3632435
EC Number:
200-386-2
MDL number:
MFCD00012807
UNSPSC Code:
12352205
eCl@ss:
34058008
PubChem Substance ID:
24899059
NACRES:
NA.55

Quality Level

200

Assay

≥98% (HPLC)

form

powder

technique(s)

HPLC: suitable

color

white to off-white

mp

214-215 °C (lit.)

SMILES string

Cl[H].Cc1ncc(CO)c(CO)c1O

InChI

1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H

InChI key

ZUFQODAHGAHPFQ-UHFFFAOYSA-N

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Application

Pyridoxine hydrochloride has been used:
  • as a vitamin supplement in the basal medium for the cultivation of Bacillus mojavensis and Bacillus subtilis strains
  • as a supplement in pre-conditioning medium/MS salts to initiate somatic embryogenesis induction of Coffea canephora seeds
  • for oral administration in piglets to study its effect on the development of homocysteinemia

Biochem/physiol Actions

Pyridoxine/Vitamin B6 plays a key role in the nervous, immune, and endocrine systems. It is also involved in the metabolic processes of proteins, lipids, and carbohydrates. Deficiency of pyridoxine may lead to convulsions and epileptic encephalopathy and result in infant abnormalities.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H318

Precautionary Statements

P280 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000403226
0000403714
0000403225
0000389839
0000387643

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Marie-Édith Côté-Robitaille et al.
Journal of nutritional science, 4, e31-e31 (2015-10-27)
Homocysteine (Hcy) is an intermediary sulphur amino acid recognised for pro-oxidative properties in several species which may weaken immune competence in piglets. In this species, there is an acute 10-fold increase of concentrations of plasma Hcy (pHcy) during the first
Vijay P Singh et al.
The Journal of organic chemistry, 78(4), 1478-1487 (2013-01-16)
Vitamin B6 is involved in a variety of enzymatic transformations. Some recent findings also indicate an antioxidant role of the vitamin in biological systems. We set out to turn pyridoxine (1a) into a catalytic chain-breaking and hydroperoxide-decomposing antioxidant by replacing
Manfred Eggersdorfer et al.
Angewandte Chemie (International ed. in English), 51(52), 12960-12990 (2012-12-05)
The discovery of vitamins as essential factors in the diet was a scientific breakthrough that changed the world. Diseases such as scurvy, rickets, beriberi, and pellagra were recognized to be curable with an adequate diet. These diseases had been prevalent
Paniz Izadi et al.
iScience, 24(8), 102822-102822 (2021-08-03)
The formation of combined electrogenic/electrotrophic biofilms from marine sediments for the development of microbial energy storage systems was studied. Sediment samples from the German coasts of the Baltic and the North Sea were used as inocula for biofilm formation. Anodic
Barbara Plecko et al.
Neurology, 82(16), 1425-1433 (2014-03-25)
To determine whether patients with pyridoxine-responsive seizures but normal biomarkers for antiquitin deficiency and normal sequencing of the ALDH7A1 gene may have PNPO mutations. We sequenced the PNPO gene in 31 patients who fulfilled the above-mentioned criteria. We were able
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