293105
Tetrahydropyran
anhydrous, 99%
Synonym(s):
Pentamethylene oxide
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About This Item
Empirical Formula (Hill Notation):
C5H10O
CAS Number:
Molecular Weight:
86.13
Beilstein:
102436
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.21
grade:
anhydrous
Assay:
99%
bp:
88 °C (lit.)
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grade
anhydrous
Quality Level
vapor density
3 (vs air)
Assay
99%
form
liquid
impurities
<0.003% water
<0.005% water (100 mL pkg)
evapn. residue
<0.0003%
refractive index
n20/D 1.42 (lit.)
bp
88 °C (lit.)
mp
−45 °C (lit.)
density
0.881 g/mL at 25 °C (lit.)
SMILES string
C1CCOCC1
InChI
1S/C5H10O/c1-2-4-6-5-3-1/h1-5H2
InChI key
DHXVGJBLRPWPCS-UHFFFAOYSA-N
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General description
Tetrahydropyran (THP) is a saturated cyclic ether. It is commonly used as a solvent in organic synthesis because of its strong hydrophobicity and low vaporization temperature, which enable easy recovery and reuse of the solvent. This makes the entire synthetic process more environmentally friendly.
Application
Tetrahydropyran can be used as a solvent in various classical organic reactions such as radical reactions, palladium-catalyzed coupling, and Grignard reactions.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Flam. Liq. 2
Supplementary Hazards
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
3.2 °F - closed cup
Flash Point(C)
-16 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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