1.00042

Acetic anhydride

for analysis EMSURE^® ACS,ISO,Reag. Ph Eur

• Synonym(s): Acetic anhydride, Acetyl acetate, Acetyl oxide
• Linear Formula: (CH₃CO)₂O
• CAS Number: 108-24-7
• Molecular Weight: 102.09
• MDL number: MFCD00008705
• UNSPSC Code: 12352106
• EC Index Number: 203-564-8
• NACRES: NA.21
• grade: ACS reagent
• form: liquid

Properties

• grade: ACS reagent
• Quality Level: 300
• Agency: reag. ISO; reag. Ph. Eur.
• vapor pressure: 4 hPa ( 20 °C)
• product line: EMSURE^®; OmniSolv^®
• Assay: ≥98.5% (GC)
• form: liquid
• autoignition temp.: 330 °C
• potency: 630 mg/kg LD₅₀, oral (Rat); 4320 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 2.0-10.2 % (v/v)
• impurities: ≤150 ppm Substances reducing potassium permanganate (as O)
• evapn. residue: ≤20 ppm
• color: clearAPHA: ≤10
• pH: 3 (20 °C, 10 g/L in H₂O)
• mp: -73 °C
• transition temp: flash point 49 °C
• density: 1.08 g/cm³ at 20 °C
• anion traces: chloride (Cl^-): ≤2 ppm; phosphate (PO₄^3-): ≤5 ppm; sulfate (SO₄^2-): ≤5 ppm
• cation traces: Al: ≤0.5 ppm; B: ≤0.02 ppm; Ba: ≤0.1 ppm; Ca: ≤0.5 ppm; Cd: ≤0.05 ppm; Co: ≤0.02 ppm; Cr: ≤0.05 ppm; Cu: ≤0.02 ppm; Fe: ≤0.1 ppm; Mg: ≤0.1 ppm; Mn: ≤0.02 ppm; Ni: ≤0.02 ppm; Pb: ≤0.1 ppm; Sn: ≤0.1 ppm; Zn: ≤0.1 ppm; heavy metals (as Pb): ≤2 ppm
• storage temp.: 2-30°C
• SMILES string: O(C(=O)C)C(=O)C
• InChI: 1S/C4H6O3/c1-3(5)7-4(2)6/h1-2H3
• InChI key: WFDIJRYMOXRFFG-UHFFFAOYSA-N

Description

General description

for analysis EMSURE^® ACS,ISO,Reag. Ph Eur

Application

• Insights into the Mechanism of Catalytic Activity of Plasmodium Parasite Malate-Quinone Oxidoreductase.: This study elucidates the catalytic mechanism of malate-quinone oxidoreductase in Plasmodium parasites, revealing potential targets for antimalarial drugs and insights into enzyme activity modulation by acetic anhydride (Ito et al., 2024).
• Adsorption simulation of 2,4-D pesticide on novel zinc-based 2-amino-4-(1H-1,2,4-triazole-4-yl)benzoic acid coordination complexes using machine learning approach.: This research presents a novel adsorption method using zinc-based coordination complexes for the removal of pesticides, where acetic anhydride plays a crucial role in the synthesis of these complexes, demonstrating an innovative approach to environmental remediation (Mansab and Rafique, 2024).

Analysis Note

Purity (GC)≥ 98.5 %Identity (IR)conformsAppearanceclearColor≤ 10 HazenChloride (Cl)≤ 2 ppmSulfate (SO₄)≤ 5 ppmPhosphate (PO₄)≤ 5 ppmHeavy metals (as Pb)≤ 2 ppmReadily carbonizable substancesconformsSubstances reducing potassium permanganate (as O)≤ 150 ppmAl (Aluminium)≤ 0.5 ppmB (Boron)≤ 0.02 ppmBa (Barium)≤ 0.1 ppmCa (Calcium)≤ 0.5 ppmCd (Cadmium)≤ 0.05 ppmCo (Cobalt)≤ 0.02 ppmCr (Chromium)≤ 0.05 ppmCu (Copper)≤ 0.02 ppmFe (Iron)≤ 0.1 ppmMg (Magnesium)≤ 0.1 ppmMn (Manganese)≤ 0.02 ppmNi (Nickel)≤ 0.02 ppmPb (Lead)≤ 0.1 ppmSn (Tin)≤ 0.1 ppmZn (Zinc)≤ 0.1 ppmEvaporation residue
≤ 20 ppm≤ 20 ppm

Evaporation Number: 0.46

Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

OMNISOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS05,GHS06
• Signal Word: Danger
• Hazard Statements: H226 - H302 - H314 - H330
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 120.2 °F - closed cup
• Flash Point(C): 49 °C - closed cup