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H3253

Sigma-Aldrich

DL-p-Hydroxyphenyllactic acid

≥97% (HPLC)

Synonym(s):

3-(4-Hydroxyphenyl)-2-hydroxypropanoic acid

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About This Item

Empirical Formula (Hill Notation):
C9H10O4
CAS Number:
Molecular Weight:
182.17
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥97% (HPLC)

SMILES string

OC(Cc1ccc(O)cc1)C(O)=O

InChI

1S/C9H10O4/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8,10-11H,5H2,(H,12,13)

InChI key

JVGVDSSUAVXRDY-UHFFFAOYSA-N

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Application

DL-p-Hydroxyphenyllactic acid is a precursor in the synthesis of rosmarinic acid that can be used for pharmaceutical and nutraceutical applications. It also exhibits antifungal activity.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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David R Gang et al.
Plant physiology, 130(3), 1536-1544 (2002-11-13)
Sweet basil (Ocimum basilicum) peltate glandular trichomes produce a variety of small molecular weight phenylpropanoids, such as eugenol, caffeic acid, and rosmarinic acid, that result from meta hydroxylation reactions. Some basil lines do not synthesize eugenol but instead synthesize chavicol
A M Dallagnol et al.
Journal of applied microbiology, 111(6), 1447-1455 (2011-09-29)
To evaluate the influence of biosynthetic precursors, intermediates and electron acceptors on the production of antifungal compounds [phenyllactic acid (PLA) and hydroxyphenyllactic acid (OH-PLA)] by Lactobacillus plantarum CRL 778, a strain isolated from home-made sourdough. Growth of fermentative activity and
Antifungal Activity of Lactobacillus pentosus LOCK 0979 in the Presence of Polyols and Galactosyl-Polyols.
Lipinska L, et al.
Probiotics and antimicrobial proteins, 6(14), 1-15 (2018)
Synthesis of 2-O-(4-coumaroyl)-3-(4-hydroxyphenyl) lactic acid, an important intermediate of rosmarinic acid biosynthesis.
Matsuno M, et al.
Chemical & Pharmaceutical Bulletin, 49(12), 1644-1646 (2001)
Emanuel Vamanu et al.
Genes, 10(7) (2019-07-18)
Non-nutritive sweeteners represent an ingredient class that directly affects human health, via the development of inflammatory processes that promote chronic diseases related to microbiota dysbiosis. Several in vitro tests were conducted in the static GIS1 simulator. The aim of the

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